Gadgetine

Exploring The Hormonal Route. Hair=life.

Seanrutty

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The thing is if you dont want to feminize you will likely not regrow much hair. Antiandrogens does not give much regrowth, otherwise castrated men at lets say 50 because of prostate cancer would regrow lot of hair and it is not the case. Your best bet is to use estradiol + dutasteride + oral minoxidil + topical minoxidil with tretinoin to get the maximum effects. At your age your hairs has been miniaturized for a long time so it doesnt even guarantee lot of regrowth but that regimen i mentioned is your best bet to recover the most hair possible in your case.

I suppose you dont want extra perfection like some of us here that are completely mental about hair so even if it doesnt gives perfect result, at your age you should be happy
Thanks for the response but one my questions is since I had reflex 20 years ago would it still happen now all these years later?? Also if finasteride caused reflex then wouldn’t dutasteride do it times like 10 lol?? See this is where it all gets confusing since everything’s different with ppl.. so let’s say someone who has reflex and up regulated now what would that person use aka me ??? Also look at the pics I sent see how the hair is wayyy thinner at the root??
 

Adri23

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Thanks for the response but one my questions is since I had reflex 20 years ago would it still happen now all these years later?? Also if finasteride caused reflex then wouldn’t dutasteride do it times like 10 lol?? See this is where it all gets confusing since everything’s different with ppl.. so let’s say someone who has reflex and up regulated now what would that person use aka me ??? Also look at the pics I sent see how the hair is wayyy thinner at the root??
Thing is even if the reflex is real, estradiol will nuke all your androgens and there will be nothing left. If you rly want to cover every angle you can add low dosage bicalutamide in addition of what I've said before.
 

Adri23

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Looking at his you seem pretty knowledgeable with hrt estrogen, is there any drug you can take while on estrogen to lower prolactin and prevent gyno?
Do you have high prolactin? If you use just estrogen it would be harder to have high prolactin. Preventing gyno on estrogens is impossible, even with stuff like raloxifen you still get some gyno and I dont think those meds would prevent gyno 100%. Best practice would be to get gyno surgery IMO
 

Seanrutty

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Thing is even if the reflex is real, estradiol will nuke all your androgens and there will be nothing left. If you rly want to cover every angle you can add low dosage bicalutamide in addition of what I've said before.
Okay random what about estrogen cream on the hairline?? I have spironolactone on hand now but it’s like a year old I was gonna pop 2 a week but I’m so unknowinable with all this.. and I don’t judge if ppl on here are using fem things for hair cool I’m down too long as I don’t start lookin like it.. I was gonna jump on 200 mg of test but I’m pretty sure then my hair will really take a sh*t.. stupid derm looked at my hair and said oh your hairs great for 41
 

Seanrutty

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Also it’s lookin so far if reflex is really and just any kinda androgen related hair loss is real once got 20029 drops it won’t matter I wonder if a guy with even terrible hair loss could just up on test and tren and still be fine with gt
 

Adri23

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Okay random what about estrogen cream on the hairline?? I have spironolactone on hand now but it’s like a year old I was gonna pop 2 a week but I’m so unknowinable with all this.. and I don’t judge if ppl on here are using fem things for hair cool I’m down too long as I don’t start lookin like it.. I was gonna jump on 200 mg of test but I’m pretty sure then my hair will really take a sh*t.. stupid derm looked at my hair and said oh your hairs great for 41
But estrogen on hairline wont do anything. Like T and DHT are much more potent than estrogen, so they will bind to AR and keep doing its stuff cause u will have lot of androgen in your blood stream. The thing about systemic e2 is to nuke your androgen production so you wont have many androgens and estrogens can exert its effects. All that said some ppl keep losing hair on hrt due to backdoor dht so dutasteride is never a bad idea
 
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Adri23

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Also it’s lookin so far if reflex is really and just any kinda androgen related hair loss is real once got 20029 drops it won’t matter I wonder if a guy with even terrible hair loss could just up on test and tren and still be fine with gt
We are not sure if it will even work as in paper. There was a huge hype with pyrilutamide and it ended up being sh*t
 

Seanrutty

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But estrogen on hairline wont do anything. Like T and DHT are much more potent than estrogen, so they will bind to AR and keep doing its stuff cause u will have lot of androgen in your blood stream. The thing about systemic e2 is to nuke your androgen production so you wont have many androgens and estrogens can exert its effects. All that said some ppl keep losing hair on het due to backdoor dht so dutasteride is never a bad idea
Okay so this is what I’ve heard now from a few ppl is this back door pathway of dht and this almost has to be going on with me.. so someone explain what is the back door pathway and why is dutasteride only mentioned but not finasteride?? Curious
 

Seanrutty

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We are not sure if it will even work as in paper. There was a huge hype with pyrilutamide and it ended up being sh*t
True.. so what can be done about reflex like I said dude Ill never forget growing upper arm hair that’s still here till this day and just shedding somedays 1000 hairs this was back when I was 21 not now.. that was reflex fully because I had super thick hair to the point the barbers would have to thin it for a fade then my dumbass jumped on finasteride and bam sex drive through the roof tons of hairs shedding out body hair growth.. there’s Noway in hell it was just a coincidence no way in hell.. I’m back on in now 1mg 3 times a week so far not the crazy sex drive but also still shedding.. what’s the month you think to say okay finasteride isn’t working?? Been on it this second time around now for 4 months with topical min mixed with tren and melatonin plus oral min 5mg plus laser cap plus scalp massager.. f*** I know this sounds nuts but if I ever had a kid and at 41 prolly not but if so I’d have to see the girls dad before f*****g and if any hair loss I’d say sorry I can’t bring a possible son into this world to go through this hair loss thing..
 

Seanrutty

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Okay so this is what I’ve heard now from a few ppl is this back door pathway of dht and this almost has to be going on with me.. so someone explain what is the back door pathway and why is dutasteride only mentioned but not finasteride?? Curious
Gotta figure out this back door pathway.. I do remember after finasteride and the reflex thing I got my hands on dutasteride real aka avodart and i remember my hair not coming out when i was pulling on it but all them years ago I can’t remember why I came off I can’t remember if I ended up with hair loss again it was so many f*****g years ago.. I had a test for lpp done 3 months ago the test came back and said negative but then I read there not always rite but f*** so I gotta go get another biopsy done..
 

Adri23

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Okay so this is what I’ve heard now from a few ppl is this back door pathway of dht and this almost has to be going on with me.. so someone explain what is the back door pathway and why is dutasteride only mentioned but not finasteride?? Curious
The red marks are basically the backdoor pathway of DHT that doesn't need T to create DHT. You can have very active 5ar1 as I do(did a genetic test) and even with estradiol alone you wont solve your hairloss cause estradiol lowers T which indirectly makes 5ar type 2 less effective cause there is no substrate to feed the 5ar2 . Dutasteride and not finasteride is mentioned because finasteride does not block 5ar1 which is responsible of dht from the backdoor pathway. Even dutasteride at standard dosages inhibit 51% of 5ar1 so maybe you will end up needing more depending on your genetics, only way to know is trying it.
 

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Seanrutty

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The red marks are basically the backdoor pathway of DHT that doesn't need T to create DHT. You can have very active 5ar1 as I do(did a genetic test) and even with estradiol alone you wont solve your hairloss cause estradiol lowers T which indirectly makes 5ar type 2 less effective cause there is no substrate to feed the 5ar2 . Dutasteride and not finasteride is mentioned because finasteride does not block 5ar1 which is responsible of dht from the backdoor pathway. Even dutasteride at standard dosages inhibit 51% of 5ar1 so maybe you will end up needing more depending on your genetics, only way to know is trying it.
Man your smart so wait where do I get this test that you got?? I didn’t know a thing even existed.. this test is called what if you don’t mind me asking
 

Adri23

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True.. so what can be done about reflex like I said dude Ill never forget growing upper arm hair that’s still here till this day and just shedding somedays 1000 hairs this was back when I was 21 not now.. that was reflex fully because I had super thick hair to the point the barbers would have to thin it for a fade then my dumbass jumped on finasteride and bam sex drive through the roof tons of hairs shedding out body hair growth.. there’s Noway in hell it was just a coincidence no way in hell.. I’m back on in now 1mg 3 times a week so far not the crazy sex drive but also still shedding.. what’s the month you think to say okay finasteride isn’t working?? Been on it this second time around now for 4 months with topical min mixed with tren and melatonin plus oral min 5mg plus laser cap plus scalp massager.. f*** I know this sounds nuts but if I ever had a kid and at 41 prolly not but if so I’d have to see the girls dad before f*****g and if any hair loss I’d say sorry I can’t bring a possible son into this world to go through this hair loss thing..
I like your point of view in not bringing new life with curse hair genetics. Have you tried dutasteride? My dumbass ADHD forgot if you mentioned it or not
 

Adri23

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Gotta figure out this back door pathway.. I do remember after finasteride and the reflex thing I got my hands on dutasteride real aka avodart and i remember my hair not coming out when i was pulling on it but all them years ago I can’t remember why I came off I can’t remember if I ended up with hair loss again it was so many f*****g years ago.. I had a test for lpp done 3 months ago the test came back and said negative but then I read there not always rite but f*** so I gotta go get another biopsy done..
So dutasteride helped you and you stopped it?

Man your smart so wait where do I get this test that you got?? I didn’t know a thing even existed.. this test is called what if you don’t mind me asking
You can search on internet genetic test for hair loss. Some ppl say it is a scam but I everything it says on that thing is true in my case.
 

Seanrutty

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I like your point of view in not bringing new life with curse hair genetics. Have you tried dutasteride? My dumbass ADHD forgot if you mentioned it or not
Yeah I tried it back then but we’re talking 2006 and for the death of me cannot remember why I stopped of how long I did it for.. the Doctor was a fruitcake he’d give me anything I asked for I said I need avodart uhhh okay bam that easy I remember trying it and remember thinking this is the end for my hair loss and grabbing my hair hard kinda pulling and either nothing came out or a few but I just can’t remember why I stopped it maybe I ended up getting tons of hair loss from it too but I just can’t remember for sh*t..
 

Adri23

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Yeah I tried it back then but we’re talking 2006 and for the death of me cannot remember why I stopped of how long I did it for.. the Doctor was a fruitcake he’d give me anything I asked for I said I need avodart uhhh okay bam that easy I remember trying it and remember thinking this is the end for my hair loss and grabbing my hair hard kinda pulling and either nothing came out or a few but I just can’t remember why I stopped it maybe I ended up getting tons of hair loss from it too but I just can’t remember for sh*t..
Maybe you can try it again. If you have enough money you can even try 2.5 mg per day. If that doesnt work then HRT is your last resource
 

Seanrutty

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I’ve not posted on here much don’t know what 414 is.. so here’s a question if reflex is real and it is.. would dutasteride cause it too since finasteride did and you can say Sean you took them both you should know but like I said I just can’t remember at all
 

Seanrutty

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And if the back door pathway is the issue then finasteride is a complete waste of time or is it still doing something?? Kinda gay to sit here and cut this 5mg into 4 pills if it’s not doing sh*t
 
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