Is There Any Hope For Future Hair Loss Treatments?

abcdefg

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Sorry that its effecting your mental well being so much. Just remember almost everyone experiences some type of hairloss eventually..... So most people never have the hair of their youth into old age. I understand your only in your twenties (I had all my hair through my 20's , though it went through many stages of looking great and looking like crap and in my 30's noticed some thinning changes.) Now in my mid 40's sure its thinned but has slowed and I can still pull a full head of hair off.(most days) Plus i have taken care of my health and look much younger for my age.

You know you do get used to it at a point. You begin to realize that the older you get no one really gives a sh*t anymore and you won't care as much anymore as well. I find myself thinking that in ten or twenty years full head of hair or not I'm gonna have aged negatively in looks and internal health in so many other ways hair will probably be the last thing on my mind. Good luck and do your best to keep it in perspective.

I would just note not everyone loses hair into old age. A smaller percent keep most if not nearly all their Norwood 1 hair from when they were 18. I think everyone is kind shooting for that ideal or at least I am. Have/keep the most hair possible. As long as your living your going to care to some degree what you look like maybe hair wont matter, but to some people it will. One persons opinion doesnt alter everyone elses.
 

Dar

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I would just note not everyone loses hair into old age. A smaller percent keep most if not nearly all their Norwood 1 hair from when they were 18. I think everyone is kind shooting for that ideal or at least I am. Have/keep the most hair possible. As long as your living your going to care to some degree what you look like maybe hair wont matter, but to some people it will. One persons opinion doesnt alter everyone elses.

Yeah I didn't say everyone...but most. There is a very small percentage of people very very small that have their juvenile hairlines until their old age and into death.....but you know they still have all the other issues associated with old age. I also understand that some people will still care to a certain degree about their hair....but when it comes to ones continued mental health its best to at least try to put it into perspective. Just offering a suggestion ....I do understand that some people may never get over it. But for many I do think it becomes less of an issue as they get older....
 

Roberto_72

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Yeah I didn't say everyone...but most. There is a very small percentage of people very very small that have their juvenile hairlines until their old age and into death.....but you know they still have all the other issues associated with old age. I also understand that some people will still care to a certain degree about their hair....but when it comes to ones continued mental health its best to at least try to put it into perspective. Just offering a suggestion ....I do understand that some people may never get over it. But for many I do think it becomes less of an issue as they get older....

I agree that the pangs of old age are many more than "simple" hair loss. Yet most people here have experienced thinning since their teens. Some of us have undergone two hair transplants ($15000) and have basically never had the "full head of hair" (most days) that you sport at 40.
So I am unsure that after suffering for decades for your hair it is really helping to think that aging is even worse.
 

Afro_Vacancy

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I agree that the pangs of old age are many more than "simple" hair loss. Yet most people here have experienced thinning since their teens. Some of us have undergone two hair transplants ($15000) and have basically never had the "full head of hair" (most days) that you sport at 40.
So I am unsure that after suffering for decades for your hair it is really helping to think that aging is even worse.

Saying that "there's something worse" is virtually never helpful, it's just condescending most of the time.
 

Dar

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Saying that "there's something worse" is virtually never helpful, it's just condescending most of the time.
I agree that the pangs of old age are many more than "simple" hair loss. Yet most people here have experienced thinning since their teens. Some of us have undergone two hair transplants ($15000) and have basically never had the "full head of hair" (most days) that you sport at 40.
So I am unsure that after suffering for decades for your hair it is really helping to think that aging is even worse.

I get that..as for my full head of hair...its not that easy. Mostly illusion. Wind or rain it pretty much doesn't look full anymore.

As for hair transplants....I'm assuming two 15000 transplants means that individual has r barely any hair on top...correct? I'm surprised a surgeon would even do that.
 

Dar

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Saying that "there's something worse" is virtually never helpful, it's just condescending most of the time.


Putting things in perspective isn't condescending....it may anger some but I was most definitely not condescending....what would you think is helpful short of a cure which looks pretty unlikely.....
 

Afro_Vacancy

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Putting things in perspective isn't condescending....it may anger some but I was most definitely not condescending....what would you think is helpful short of a cure which looks pretty unlikely.....

Any additional treatment at reasonable cost is helpful.

I'm looking forward to Brotzu/Fidia.
 

kuba197

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Hoping that brotzu, cb and maybe high density hair transplant deliver me to Tsuji's hair regeneration method...
 

Roberto_72

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I get that..as for my full head of hair...its not that easy. Mostly illusion. Wind or rain it pretty much doesn't look full anymore.

So most of your hair issues would be solved by not living in Chicago. I think this gives you a perspective that is very privileged than 99% of the users here. I envy you.

As for hair transplants....I'm assuming two 15000 transplants means that individual has r barely any hair on top...correct? I'm surprised a surgeon would even do that.

"15000 transplants" means nothing, it is not what I wrote. I wrote "$/€ 15000 in transplants" meaning that hair transplants cost a lot. With two transplants you get 3-4-5000 grafts (depending on the technique and the donor area and the surgeon), which is a number any surgeon would do and why should he not?

Putting things in perspective isn't condescending....it may anger some but I was most definitely not condescending....what would you think is helpful short of a cure which looks pretty unlikely.....
You say you do not want to sound condescending, but you have hair (except when it rains) and come here to write that cures that have not been tried yet seem "unlikely" to you. To what purpose?
 

Bagels

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Right now the best you can probably do a combination of experimental and common treatments to maintain your hair and maybe get some regrowth.

finasteride/dutasteride, minoxidil, RU/CB, seti, pge2. Obviously, this is a big time and money investment so we're not at the magic pill by any means.
For future, the two big at home treatments we're waiting for are Samumed growth stimulant and (especially) Pulmagen ADC formula which is a CRTH2 antagonist, working similar to seti but better.
 

champpy

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Does anyoneknow when (or if) pulmagen is going,to be released? What phase of trials is it even in?
 

Desmond_84

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I don't get it. Their science is sound. A Japanese firm is pouring money into their lab. They've built trial facilities in Japan and Europe. But they just will NOT begin the trials! I thought trials were the red tape before a therapy makes it to general public but it seems the red tape needs another red tape! So much bureaucracy and time wasting it makes me sick!

If they don't pull through these issues by the end of 2016 then we will not have access to any new therapies till at least 2020! So depressing :(
 

WangMQ

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The current angles we have (legit or not):

1. 5AR inhibitors-finasteride/dutasteride: Obviously flawed and unsafe sh*t.

2. Anti-androgens-RU/CB/S-equol and such: Sides from RU have been more or less a consensus. I personally don't put a lot of stocks in this angle. A lot of AAs have long been there but the problem is systemic absorption. When you put a potent AA like RU onto your scalp you WILL get systemic absorption to some extent and in long term it will fxxk you up, therefore will never become publicly available. When you use a less potent AA it's not enough to halt your hair loss. When you use compounds like CB with fast metabolizing rate it might be side free but not so strong at keeping your hair for the same reason.

(My experience with AAs sometimes make me think: maybe instead of finding miracle drugs, they should spend time on drug delivery, e.g. coming up with some vehicles that keep the topical AAs in your scalp just like what was clamed of Hasson & Wong's formulation, which unfortunately seems to have systemic sides too)

3. PGD2/CRH2 inhibitors-Seti/OC/TM: Up till now reports about sides are minor, but since we're quite sure PGD2 and its receptors have so many things to do with our body and sleep problems are already coming up from seti/OC users, I tend to stay reasonably skeptic to them. Remember how they said inhibiting your 5AR won't be such a big deal?

4. Growth stimulants-minoxidil/Copper Peptide/Stemoxydine/PGE2/SM and on and on: In short, without a solid preventative method to halt or stablize your hairloss, I think these are not our primary concern. Not bad to use and minor sides though. And I honestly wish one day a growth stimulant potent enough to halt male pattern baldness alone will come out.

5. Hair transplant: Table turning but meaningless if you can't maintain to start with.

6. Stem cell methods/PRP/Acell/Histogen/Kerastem-Doesn't deal with the root of androgens, but kind of deals with another root of hairloss by repairing your scalp and follicles. Seems that this angle inevitably needs repetitive treatment and that together with the cost is problematic. No sides for sure.

When you see a new treatment just try to put it into these catagories and it won't be hard to estimate from a larger perspective.

Personally I'm kind of getting tired of messing with all these enzymes and hormones...When you're talking about life long commitment, it's just so hard to stay away from sides.
 

whatevr

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I suppose feeling like a eunuch for the better part of the year to move back to almost NW1 would even be worth it if there was no permanent (or severely unhealthy) side effects.
 

abcdefg

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We are on a hair loss forum so yes we will age, but here we are concerned with keeping hair regardless. We have years to wait for better stuff, and other things could easily end up not working. So do what you can now with what exists versus just hoping for better stuff.
Do what you can now finasteride,dutasteride + RU or CB + minoxidil if you can afford it all and that is all you can do. Deal with the health risks and sides or accept it. Pretty simple really
 

hilbert

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The current angles we have (legit or not):

1. 5AR inhibitors-finasteride/dutasteride: Obviously flawed and unsafe sh*t.

2. Anti-androgens-RU/CB/S-equol and such: Sides from RU have been more or less a consensus. I personally don't put a lot of stocks in this angle. A lot of AAs have long been there but the problem is systemic absorption. When you put a potent AA like RU onto your scalp you WILL get systemic absorption to some extent and in long term it will fxxk you up, therefore will never become publicly available. When you use a less potent AA it's not enough to halt your hair loss. When you use compounds like CB with fast metabolizing rate it might be side free but not so strong at keeping your hair for the same reason.

(My experience with AAs sometimes make me think: maybe instead of finding miracle drugs, they should spend time on drug delivery, e.g. coming up with some vehicles that keep the topical AAs in your scalp just like what was clamed of Hasson & Wong's formulation, which unfortunately seems to have systemic sides too)

3. PGD2/CRH2 inhibitors-Seti/OC/TM: Up till now reports about sides are minor, but since we're quite sure PGD2 and its receptors have so many things to do with our body and sleep problems are already coming up from seti/OC users, I tend to stay reasonably skeptic to them. Remember how they said inhibiting your 5AR won't be such a big deal?

4. Growth stimulants-minoxidil/Copper Peptide/Stemoxydine/PGE2/SM and on and on: In short, without a solid preventative method to halt or stablize your hairloss, I think these are not our primary concern. Not bad to use and minor sides though. And I honestly wish one day a growth stimulant potent enough to halt male pattern baldness alone will come out.

5. Hair transplant: Table turning but meaningless if you can't maintain to start with.

6. Stem cell methods/PRP/Acell/Histogen/Kerastem-Doesn't deal with the root of androgens, but kind of deals with another root of hairloss by repairing your scalp and follicles. Seems that this angle inevitably needs repetitive treatment and that together with the cost is problematic. No sides for sure.

When you see a new treatment just try to put it into these catagories and it won't be hard to estimate from a larger perspective.

Personally I'm kind of getting tired of messing with all these enzymes and hormones...When you're talking about life long commitment, it's just so hard to stay away from sides.

wrong logical link for cb. it can work locally and become ineffective systemically. there's enough theory and pocs about it, and so far i'm seeing it on my head and body (knock wood...)
 

Mr White

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Why does a new treatment need to be better than minoxidil if it uses a different pathway? They should just package it with minoxidil. Plus, minoxidil has a mediocre response rate.


I couldn't agree more. Combination therapy is the way to deal with male pattern baldness, maybe Fidia should add minoxidil to Brotzu's formula for improved results.
 

Mr White

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Uhhh I don't even know why I started this thread it just makes me depressed. I'm so tired of this sh*t, always waiting, nothing ever comes to fruition...delays, set backs, bullshit, lies, snake oil. It's really hitting me hard at the moment and there is absolutely f*** all I can do about it. [...]

I guess we are all impatient but we have reasons to be pleased and optimistic. We are the first generation in history that was able to benefit from baldness treatments that really do work (minoxidil, finasteride) and the future looks promising.

I started losing my hair at the age of 17, today I'm 40 and still a nw2 thanks to Proscar.
 

Swoop

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I don't get it. Their science is sound. A Japanese firm is pouring money into their lab. They've built trial facilities in Japan and Europe. But they just will NOT begin the trials! I thought trials were the red tape before a therapy makes it to general public but it seems the red tape needs another red tape! So much bureaucracy and time wasting it makes me sick!

If they don't pull through these issues by the end of 2016 then we will not have access to any new therapies till at least 2020! So depressing :(

Hope for Shisheido too ASAP...

http://news.biglobe.ne.jp/it/0627/mnn_160627_5205821981.html

Apparently they are moving forward :), all that matters really.
 
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