Leave Your Hormones Alone

Fat-Elvis

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JWM said:
Michael Barry

spironolactone twice a day? Yikes, I could probably only manage once a day. The stuff makes my diffuse thinning look awful in the morning.
I hate using that stuff during the day as well, but I've heard it's not really effective enough to be worth using unless you use twice a day?
 

bubka

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vq0 said:
waseda regime doesn't involve topical SODs and apple poly. I think these two things are potent enough to stop hair loss if applied 2x a day. Does anyone have experience with these two supps?
seriously, who is going to actually religiously apply something 2x a day for the rest of their lives in hopes of regrowing hair which is probably no better than a wish at best???

what a bs post...

post481071087687jp3.gif
 

Bryan

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JWM said:
spironolactone twice a day? Yikes, I could probably only manage once a day. The stuff makes my diffuse thinning look awful in the morning.

This is where I always step in and point out that in some of the animal studies that successfully tested topical spironolactone, it was applied only once a day, and sometimes not even over weekends.

Bryan
 

IBM

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One thing i dont understand: my best erections and ejaculations was in youth (14 to 18 ) and still i had great head of hair (16 was my best). 5-alpha-reductase was there, testosterone was there, i dont understand why you go bald after puberty? Why some go bald at 40's and not at 18's.
 

Bryan

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For a combination of reasons, including at least the following two:

1) Damage to hair follicles is slow and accumulative.

2) Judging by experiments with stumptailed macaques, scalp hair follicles start to become sensitive to androgens druing or after puberty. They aren't simply born that way, apparently.

Putting #1 and #2 together above, you can see why damage begins during/after puberty, then slowly accumulates and worsens as the years go by.

Bryan
 

Bryan

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Fat-Elvis said:
JWM said:
**In my best John Hurt voice**

"I am not an animal!!!"
Ahh dammit I was gonna do that.

Yeah, but did it ever occur to you guys that it's even MORE impressive than it is for humans that those little laboratory rodents with higher metabolic rates would be sensitive to only once-per-day applications of topical spironolactone?

Bryan
 

IBM

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Bryan said:
For a combination of reasons, including at least the following two:

1) Damage to hair follicles is slow and accumulative.

2) Judging by experiments with stumptailed macaques, scalp hair follicles start to become sensitive to androgens druing or after puberty. They aren't simply born that way, apparently.

Putting #1 and #2 together above, you can see why damage begins during/after puberty, then slowly accumulates and worsens as the years go by.

Bryan

I see. So DHT has always been with us since the beginning?
 

SnowRider22

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I have no problem taking a pill once a day for the rest of my life if it allows me to keep my hair and does not damage my body in any way.
 

michael barry

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spironolactone once a day is of course, better than no spironolactone.


However its generally recommended to use it two times a day, at least 8 hours apart, because it breaks down in the skin, etc.


Im going to test a few more anti-androgens on my beard hair until I hang up testing stuff. I had put revivogen to a test on a wrist over a year ago to great results (lot less hair) however, wrist skin might be more permeable than thicker scalp skin. I think the skin of the neck and beard might give me a better idea of how various anti-androgenic topicals might effect the scalp. I might buy a little spironolactone and apply it twice a day within the next month or so and see what I get up there.


Otherwise, like everyone else....................Im waiting for cloning.



On LEF prox-n. It smells funny. You can just "tell" its watered down somewhat. Their version of his shampoo is more watery, but it sure as hell spreads out better.


As I piddle around with a few anti-androgens on beard and body hair.....I'll let you guys know if I get a good result with anything in the next couple of months. The good thing about using beard hair is that I shave there and should get a good idea in just 2-3 weeks if Im slowing growth. A month at most.



JWM....................you have a solid regimine. 15 years ago no-one one earth would have had one that good, no matter how dedicated.
 
G

Guest

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michael barry,

i really think that avodart once a day is all that people need to maintain their hair for decades and decades. this other stuff is great for regrowth and stuff but if all people want is to maintain, then avodart and maybe nizoral two-three times a week is really all that 99% of people need.
 
G

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JayMan said:
michael barry,

i really think that avodart once a day is all that people need to maintain their hair for decades and decades. this other stuff is great for regrowth and stuff but if all people want is to maintain or maybe get a bit of regrowth, then avodart and maybe nizoral two-three times a week is really all that 99% of people need.
 

Nick4441

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Jayman,

Are you really convinced that dutasteride is the ultimate and much better than finasteride?

I'm still just less than 2 months in on finasteride but losin hair at high rate and dream of holding ground and i'm not convinced that's going to happen...3 months of Saw Palmetto did nothing before it. it may be that for some DHT reduction is not the fix....I continue to be patient and try to keep faith but I think realisation is setting in and its sad coming to terms with looking 5 yrs older than you are without hair than 5yrs younger with hair.

For some this thing kicks in with real aggression and stopping it seems very difficult. I think its easier if your rate of loss is much slower...Bugger.
 

WorldofWarcraft

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vq0 said:
DHT is not the culprit in male pattern baldness. Fibrosis caused by something that DHT does to the cell results in the attack of the follicle by your immune system and is visible as miniaturization. Is it not entirely possible that the cycles of maintenance and shedding on hormonal suppresants like finasteride and dutasteride result from our bodies compensating for an increase in testosterone. Suppressing DHT is a quick fix for a lifelong condition and even the celebrated 5-year propecia study shows that hair will continue to deteriorate. Bodily DHT deprivation is not worth the costs and lacks benefit unless you have BPH.

The only way to stop the balding process dead in its tracks is to stop the inflammation of the hair follicle. Suppression of DHT is one way to do this but there are many others. Below I have listed proven anti-fibrosis substances. Feel free to add to the list and discuss those I have listed. If anyone has had success with these please say which product you attribute it to and the rest of your regimine as well.

Anti-inflammatories
Essential Fatty Acids (Flax Oil, others)
Garlic
Emu Oil

Anti-oxidants
SOD (topical Cu/Zn and internal gliSODin)
SOD mimetics (TEMPOL)
Circumin
Grape Seed Extract
Green Tea
Fruits and Veggies

Could an anti-fibrotic regimine in combination with topical spironolactone be more effective than one based on hormone reducing drugs. I think it can and with products like Graftcyte selling for $150 I think there are people in the pharmaceutical industry that know this and are keeping quiet.

JAYMAN, PLEASE BAN THIS GUY
 

michael barry

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Jayman,

Im pretty sure youre right about dutasteride if one catches baldness as they are just beginning to lose ground up there. The addition of nizoral would seemingly be all one needed.



I do however, want "some" dht personally. Im using finasteride.

Im sensitive to some individuals who I have encountered that have had trouble with finas and dutas also. Some guys seemingly rely on DHT more than others to function. Some guys really do complain of fatigue, gyno, libido loss, weight gain, etc.

I am glad that you are having success with dutas and aren't experiencing sides. Perhaps someday science will produce a pill to deal with side effects of 5Ar-inhibitors so everyone can benefit from them
 
G

Guest

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WorldofWarcraft said:
vq0 said:
DHT is not the culprit in male pattern baldness. Fibrosis caused by something that DHT does to the cell results in the attack of the follicle by your immune system and is visible as miniaturization. Is it not entirely possible that the cycles of maintenance and shedding on hormonal suppresants like finasteride and dutasteride result from our bodies compensating for an increase in testosterone. Suppressing DHT is a quick fix for a lifelong condition and even the celebrated 5-year propecia study shows that hair will continue to deteriorate. Bodily DHT deprivation is not worth the costs and lacks benefit unless you have BPH.

The only way to stop the balding process dead in its tracks is to stop the inflammation of the hair follicle. Suppression of DHT is one way to do this but there are many others. Below I have listed proven anti-fibrosis substances. Feel free to add to the list and discuss those I have listed. If anyone has had success with these please say which product you attribute it to and the rest of your regimine as well.

Anti-inflammatories
Essential Fatty Acids (Flax Oil, others)
Garlic
Emu Oil

Anti-oxidants
SOD (topical Cu/Zn and internal gliSODin)
SOD mimetics (TEMPOL)
Circumin
Grape Seed Extract
Green Tea
Fruits and Veggies

Could an anti-fibrotic regimine in combination with topical spironolactone be more effective than one based on hormone reducing drugs. I think it can and with products like Graftcyte selling for $150 I think there are people in the pharmaceutical industry that know this and are keeping quiet.

JAYMAN, PLEASE BAN THIS GUY

Being stupid isn't a bannable offense.
 
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