Lots Of New Info On Follica's Website

[thomps1523]

Yes let me clarify one thing. Dermabrasion and microdermabrasion have been done for the last decade or two to reduce acne scarring. It is something that is even being offered in cosmetic studios and salons not just clinics. If done by a skilled technician it is something very safe.
There are contraptions like
REVIDERM Skin Peeler which can depending on the depth of skin you want to treat operate on epidermis and dermis of the skin.
I think we should concentrate on what kind of compound Follica plans to use. Because even if the signaling following the dermabrasion kicks in we still need a good enough compound to jump start growth.I'm not sure minoxidil is strong enough to act on follicles that have degraded due to DHT. Back in 2008 Follica was playing with lithium compounds but that got them nowhere.

Any idea if we want to do the whole scalp are we going to have to shave our heads?

 

[KO1]

Yes let me clarify one thing. Dermabrasion and microdermabrasion have been done for the last decade or two to reduce acne scarring. It is something that is even being offered in cosmetic studios and salons not just clinics. If done by a skilled technician it is something very safe.
There are contraptions like
REVIDERM Skin Peeler which can depending on the depth of skin you want to treat operate on epidermis and dermis of the skin.
I think we should concentrate on what kind of compound Follica plans to use. Because even if the signaling following the dermabrasion kicks in we still need a good enough compound to jump start growth.I'm not sure minoxidil is strong enough to act on follicles that have degraded due to DHT. Back in 2008 Follica was playing with lithium compounds but that got them nowhere.

Not so fast, just like dermarolling/stamping and dermabrasion are two separate things. Dermabrasion and microdermabrasion are again two separate things. Dermabrasion is done in a clinic while under anesthesia by a doctor. Not so with microdermabrasion.

Follica's procedure is likely Dermabrasion proper, in a doctor's office, under anesthesia.

 

[thomps1523]

I'm wondering if they'll even offer treating the full scalp due to dermabrasion being a bit more severe than microneedling. Also not sure I'd want to care for my entire scalp while healing, but who knows how severe it'll really be.

That's kind of what I'm wondering...

 

[QueryKickBan]

That's kind of what I'm wondering...

I don't think they would take on an entire scalp at once, since that would massively increase the risk of an infection, which is definitely something you want to avoid.

 

[GotHair?]

Not so fast, just like dermarolling/stamping and dermabrasion are two separate things. Dermabrasion and microdermabrasion are again two separate things. Dermabrasion is done in a clinic while under anesthesia by a doctor. Not so with microdermabrasion.

Follica's procedure is likely Dermabrasion proper, in a doctor's office, under anesthesia.

Depends which country are you from . In my country beauty shops are doing microdermabrasion. Unless they are falsely advertising which is I admit possible.

 

[KO1]

Depends which country are you from . In my country beauty shops are doing microdermabrasion. Unless they are falsely advertising which is I admit possible.

Please reread my post. MD is different from D.

 

[Xaser94]

https://twitter.com/Follica_Bio?lang=en

follica's twitter page is finally active

 

[Noisette]

Good find as always !

 

[KO1]

Reading material for those interested:
http://www.medscape.com/viewarticle/807243_2

Key to remember here is that Follica is doing skin disruption and packaging the process into a device. Since dermabrasion is already done as a surgical procedure, it may have an easier pathway.

 

[Beowulf]

At some point he has to decide he's never going to do anything worthwhile, so he needs to cash in on something. His name isn't worth anything if he never does anything. I'm just playing devil's advocate here. I think he does have something with this. It's just not a cure. We have already seen people get great results from wounding. Hopefully he has perfected the protocol, and we will see even better results.

He is the head of dermatology at UPenn, I mean surely that says a lot right?

The thing I find a bit stupid about Cotsarelis at this point is that his university is making massive gains with CRISPR and he doesn't seem to be throwing his hat in the ring with those guys.

http://www.sciencemag.org/news/2016...m=facebook-text&utm_campaign=humancrispr-5197

Hopefully some smart, brave molecular biologist will step forward and banish the dermatologists and their shaky promises away forever!

 

[hellouser]

This is actually a really big deal; it means they are gearing up for a PR campaign. They wouldn't bother with this if they weren't preparing to push a product. Also, until now, Follica was running silent; this is a major change of their behavior.

I thought best case for Follica was within four years, but now I think it may be sooner.

They're aiming for 2018 commercial release.

 

[luiza]

I know no one is sure about how this is gonna work but... They say they can create new follicles with this technique... So is it too optimistic or unwise to think they can give a full head of hair to a NW7? Maybe by combining it with another treatment (eg Histogen)..
My hair loss is diffuse (I'm a lady ), so I'm gonna need it all over my head...

By the way, does anyone know if they have done any human trials? They're so secretive...

 

[hellouser]

I know no one is sure about how this is gonna work but... They say they can create new follicles with this technique... So is it too optimistic or unwise to think they can give a full head of hair to a NW7? Maybe by combining it with another treatment (eg Histogen)..
My hair loss is diffuse (I'm a lady ), so I'm gonna need it all over my head...

By the way, does anyone know if they have done any human trials? They're so secretive...

They have, otherwise they wouldn't be releasing this in a little over a year's time.

 

[hellouser]

So is Histogen, but neither of them are going to make it. First quarter 2019, or it never happens for either company.

You know this how?

 

[Beowulf]

I know no one is sure about how this is gonna work but... They say they can create new follicles with this technique... So is it too optimistic or unwise to think they can give a full head of hair to a NW7? Maybe by combining it with another treatment (eg Histogen)..
My hair loss is diffuse (I'm a lady ), so I'm gonna need it all over my head...

By the way, does anyone know if they have done any human trials? They're so secretive...

This document says it can create more than 100 hairs her cm squared, which is basically normal density. Only problem is some are vellus, but minoxidil can take care of that. The thing I want to know is if you can wound an area without destroying hair follicles that are already there, presumably they can't if they need to wound deep enough for an entirely new follicle to be created, they'd probably have to wound deep enough to destroy any current follicles.

 

[hellouser]

This document says it can create more than 100 hairs her cm squared, which is basically normal density. Only problem is some are vellus, but minoxidil can take care of that. The thing I want to know is if you can wound an area without destroying hair follicles that are already there, presumably they can't if they need to wound deep enough for an entirely new follicle to be created, they'd probably have to wound deep enough to destroy any current follicles.

It's unlikely it'll affect existing follicles. If anything, it'd probably benefit them. They wouldnt work on a treatment that has that kind of compromise.

 

[Beowulf]

It's unlikely it'll affect existing follicles. If anything, it'd probably benefit them. They wouldnt work on a treatment that has that kind of compromise.

If it did, it could be used to heal fully balded areas.

I hope your right though, I'd gladly spend the rest of my life getting my cut up if it would grow my hair back!

 

[hellouser]

Because Histogen has yet to keep a timeline, and Follica is a complete unknown. If neither make it to market by 2019, they'll be significantly behind schedule, which means they couldn't make it work as proposed and likely aren't going to succeed. That being said, I believe Follica will definitely release a product, as all the documentation looks legit and the people behind the company are, too. I'm nearly as confident that Histogen won't, for the inverse reasons I gave for Follica.

There's still no mention of the pharmaceutical portion of Follica's protocol. If it's just minoxodil as so many believe, then 2018 is possible; if it's proprietary, it would have to be in or completed Phase III trials now to come out in two years, and there is no indication of either.

But that's YOUR speculation. Both have stated they're aiming for 2018 which is all anyone can go by.

 

[That Guy]

I'm not going to get into an argument with you over Histogen - you're too emotionally invested in them to be rational about it.

said the conspiracy theorist

 

[hellouser]

And Histogen has already missed one target, so why should I take their word for it? Their track record suggests they can't keep timelines, so it's not exactly speculation to expect them to miss another one. Every aspect of that company smells fishy, from their missed timelines and questionable photographs to their third-world trial locations and circumventive commercialization strategy.

You're still speculating. Can't refute that.

I'm not going to get into an argument with you over Histogen - you're too emotionally invested in them to be rational about it.

That's a lie, LOL. Why would you even say something like that?

As for Follica, you're correct, I'm assuming everything won't go exactly as they plan, which is usually what happens to pharmaceutical startups. But as I said, if their "secret sauce" is just minoxidil, then there is a chance they make it in 2018. I certainly hope that's the case.

You're speculating AGAIN.