Replicel Is On Fire Lately — Data In Feb.

pegasus2

Senior Member
My Regimen
Reaction score
4,513
I guess I don't see why it would get canned especially in Japan. They pay millions to go through phase 2, they don't need to necessarily go through phase 3 before going to the market... I get if they then had to pay for phase 3 trials, and regrowth wasn't great. This looks to be a helpful treatment with great benefits, and the investment for sheisido has been made with phase 2 trials... why not bring it to the market?

I believe they still have to run another trial in Japan, they just get to release it before they are finished if the preliminary data is posititive. I would actually be shocked if it doesn't make it to market with Shiseido. Replicel is the one that is less certain, but I think they are likely to make it eventually after they start receiving payments from Shiseido, it could just take a long time. I don't care because I plan to fly to Japan and have this done ASAP, regardless of Replicel's timeline.
 

nameless

Banned
Reaction score
1,091
I believe they still have to run another trial in Japan, they just get to release it before they are finished if the preliminary data is posititive. I would actually be shocked if it doesn't make it to market with Shiseido. Replicel is the one that is less certain, but I think they are likely to make it eventually after they start receiving payments from Shiseido, it could just take a long time. I don't care because I plan to fly to Japan and have this done ASAP, regardless of Replicel's timeline.

And keep in mind that Replicel surely showed Shiseido the 6-month results before Shiseido got on board with Shiseido's technology. So Shiseido must have known that there's a chance that Replicel's treatment may only arrest hair loss when they used resources to set-up a sophisticated building for mass production of cells to treat many patients specifically with Replicel's tech, and initiating clinical trials. Of course they're hoping they can get more regrowth by changing the dose and using repeat treatments, but I think they likely decided that arresting hair loss would be sufficient to take the treatment to market.
 
Last edited:

thomps1523

Established Member
Reaction score
298
Also, it's my understanding that Shiseido has spent big money on securing land and erecting a big sophisticated building and set that building up for the sole purpose of mass processing cells for the Replicel treatment. I don't think Shiseido will walk away from this effort unless test subjects lose hair while on the Replicel treatment. As long as the treatment at least arrests hair loss I think Shiseido will bring it to market.

Agreed, but I will add along with that, that you would have to assume sheisido did their due diligence in demanding data from replicel's phase one trials, and felt confident enough that patients wouldn't lose their hair before making such a large investment in a treatment that had a few years worth of trial data available.
 

thomps1523

Established Member
Reaction score
298
I believe they still have to run another trial in Japan, they just get to release it before they are finished if the preliminary data is posititive. I would actually be shocked if it doesn't make it to market with Shiseido. Replicel is the one that is less certain, but I think they are likely to make it eventually after they start receiving payments from Shiseido, it could just take a long time. I don't care because I plan to fly to Japan and have this done ASAP, regardless of Replicel's timeline.

Yeah they'll still have to do another phase of trials, but they can begin profiting off of it after the early release is granted while they do those trials. I agree that replicel releasing elsewhere is a big question, but I think the21st century cures act could potentially be huge for replicel in America if replicel can pick up some coin through sheisido.
 

inmyhead

Senior Member
Reaction score
1,019
I'm not saying Replicel's treatment will definitely get terminated if it only arrests hair loss. I'm just saying that it's possible. Investors want WOW regrowth, not just stabilization.

But Shiseido owns the Asian rights to this treatment and Shiseido isn't a struggling company that's ruled solely by investor's whims. Plus, the Japanese people are sick of hair loss, finasteride is the only treatment that can arrest hair loss, and there are drawbacks to taking finasteride.

So I do think there's a better than even chance that Shiseido could take Replicel's technology all the way to market in Japan, if Shiseido can establish that the tech will definitely arrest hair loss.

Why the f*** i always thought that shiseido is based in china lol
 

tress_dreams

Member
Reaction score
24
Shiseido Cell-Processing and Expansion Center (aka SPEC). The fact that they built a labaratory specific for this purpose should tell everyone that they are not messing around.

You can google street view the office. The pictures are outdated as it's been finished for awhile.
1-5-5, Minatojimaminamimachi, Chuo-ku, Kobe-shi, Hyogo 650-0047, Japan

I don't think they realize that an orderly mob of bald foreigners will be camping out in front of the SPEC building waiting for treatment. They may not be aware of our black fridays. ;)
 

Armando Jose

Senior Member
My Regimen
Reaction score
1,004
Of course they're hoping they can get more regrowth by changing the dose and using repeat treatments, but I think they likely decided that arresting hair loss would be sufficient to take the treatment to market.

Arresting the process of alopecia is not a baladi either, because it supposes that they must continue to renew the hair that is naturally lost continuously. The renewal system must be operational, does not mean that new hairs are born but if you keep those you have.
 

Ghostofchristmas

Member
My Regimen
Reaction score
23
Watch out for brotzu lotion
 

Attachments

  • IMG_7287.jpg
    IMG_7287.jpg
    174.6 KB · Views: 425

GodisnotBald

Member
Reaction score
10
Hye guys,

After having read some negative comments, I invested some hours investigating (1) Shiseido/Replicel and (2) Kyocera/RIKEN tandems as well as (3) L'Oreal 3-D solution.

I tend to think that our situation (namely, suffering from the nuts syndrom; having our head shifting from a hairy crown to damn male balls) is going to be solved. Norwood 1 is coming.

1) Well-suited investors & developers:
The fact that giants are currently financing these studies (Shiseido, Kyocera & L'Oreal) is an amazing indicator as usually shitty studies (more risky, less potential positive output) are mainly financed by public funds (it is a fact). On the other hand, Hairloss has not benefited from a "momentum" such as some tech companies did before having their R&D pipeline financed by private companies. This is a secound positive indicator: hairloss technologies in itself are not benefiting from a speculation factor. So only scientific evidences & success potential are priced in their investment offer. Not a trend premium; a good point for us.

2) A healthy competition:
Three market segments are being covered : Norwood-fucked up (namely, 4-7) and Norwood-shitty (3) and even Norwood-ok (1-2) for all 3 solutions and are potential competitors (even if we can predict L'Oreal as being a well suited actor for people being savagely hit by the sickness at the moment and would'nt invest much money in (1) & (2), or people who just want to modify a stabilized hairline, still a huge market ) . As a result, all these companies are just shitting in their pant to be the first standard of care in the industry and replace the Big 3.

Note: It seems that there are more synergies between (1) Shiseido/Replicel and (2) Kyocera/RIKEN tandems which even have labs in the same street. Some colusion may be on the line. Nice thing for us.

3) The first cellular products developed for one purpose: ending Baldness. A completly different situation than with Rogaine & Finasteride:

Rogaine & Fina had other purpose than curing the Head-Balls-Syndrome (aka bald male pattern) and in the end, they created a market which was dominated by snake-oil crap, hair transplants & shitty wigs. In a way, they oppened the door to Giants like L'Oreal to make the big move: if a pseudo solution like the Big 3 could raise billions in few decades, the right solution would make them rich. The only thing was to wait to the right moment and current R&D development will permit to propose the first process purposely funded to cure baldness. This is a key breakthrough: it's the first time in history of the mankind that an optimal process is being developed for the only purpose of curing (and not having a half solution) the Head-Nuts-Syndrome aka andro alopecia

4) Let be brief: proof of concepts are all done for these 3 solutions. Preclinical done. Phase I Phase II on the move; this is good news. Lot of risk of failure is behind us.

5) Highly ranked specialists working to develop R&D pipeline

Having a Lee Buckle as CEO at RepliCel is a good thing and the company is covered by analyst Douglas Loe who is a good lad, José Cotovio from L'Oreal is quite bullish (he's bald btw) which means a lot , and seing all the names of the Japanese experts, you know our hopes are in good hands, not as in the snake-oil-products period (10 years ago).

All these people would never put their reputation at stake in a shity project; business is like that.


So, on a nutshell: our hopes are backed by relevant success factors this time (INCREDIBLE financial support, great management, experts with strong reputation, succesful proof of concepts & Phase I, and great approaches being either cellular or biologic) . Which is a first time in history of baldness.





 
Last edited:

Captain Rex

Established Member
My Regimen
Reaction score
540
Hye guys,

After having read some negative comments, I invested some hours investigating (1) Shiseido/Replicel and (2) Kyocera/RIKEN tandems as well as (3) L'Oreal 3-D solution.

I tend to think that our situation (namely, suffering from the nuts syndrom; having our head shifting from a hairy crown to damn male balls) is going to be solved. Norwood 1 is coming.

1) Well-suited investors & developers:
The fact that giants are currently financing these studies (Shiseido, Kyocera & L'Oreal) is an amazing indicator as usually shitty studies (more risky, less potential positive output) are mainly financed by public funds (it is a fact). On the other hand, Hairloss has not benefited from a "momentum" such as some tech companies did before having their R&D pipeline financed by private companies. This is a secound positive indicator: hairloss technologies in itself are not benefiting from a speculation factor. So only scientific evidences & success potential are priced in their investment offer. Not a trend premium; a good point for us.

2) A healthy competition:
Three market segments are being covered : Norwood-fucked up (namely, 4-7) and Norwood-shitty (3) and even Norwood-ok (1-2) for all 3 solutions and are potential competitors (even if we can predict L'Oreal as being a well suited actor for people being savagely hit by the sickness at the moment and would'nt invest much money in (1) & (2), or people who just want to modify a stabilized hairline, still a huge market ) . As a result, all these companies are just shitting in their pant to be the first standard of care in the industry and replace the Big 3.

Note: It seems that there are more synergies between (1) Shiseido/Replicel and (2) Kyocera/RIKEN tandems which even have labs in the same street. Some colusion may be on the line. Nice thing for us.

3) The first cellular products developed for one purpose: ending Baldness. A completly different situation than with Rogaine & Finasteride:

Rogaine & Fina had other purpose than curing the Head-Balls-Syndrome (aka bald male pattern) and in the end, they created a market which was dominated by snake-oil crap, hair transplants & shitty wigs. In a way, they oppened the door to Giants like L'Oreal to make the big move: if a pseudo solution like the Big 3 could raise billions in few decades, the right solution would make them rich. The only thing was to wait to the right moment and current R&D development will permit to propose the first process purposely funded to cure baldness. This is a key breakthrough: it's the first time in history of the mankind that an optimal process is being developed for the only purpose of curing (and not having a half solution) the Head-Nuts-Syndrome aka andro alopecia

4) Let be brief: proof of concepts are all done for these 3 solutions. Preclinical done. Phase I Phase II on the move; this is good news. Lot of risk of failure is behind us.

5) Highly ranked specialists working to develop R&D pipeline

Having a Lee Buckle as CEO at RepliCel is a good thing and the company is covered by analyst Douglas Loe who is a good lad, José Cotovio from L'Oreal is quite bullish (he's bald btw) which means a lot , and seing all the names of the Japanese experts, you know our hopes are in good hands, not as in the snake-oil-products period (10 years ago).

All these people would never put their reputation at stake in a shity project; business is like that.


So, on a nutshell: our hopes are backed by relevant success factors this time (INCREDIBLE financial support, great management, experts with strong reputation, succesful proof of concepts & Phase I, and great approaches being either cellular or biologic) . Which is a first time in history of baldness.
tumblr_mowjer5HDD1s9frcro1_500.gif
 

NorwoodGuardian

Established Member
Reaction score
184
Hye guys,

After having read some negative comments, I invested some hours investigating (1) Shiseido/Replicel and (2) Kyocera/RIKEN tandems as well as (3) L'Oreal 3-D solution.

I tend to think that our situation (namely, suffering from the nuts syndrom; having our head shifting from a hairy crown to damn male balls) is going to be solved. Norwood 1 is coming.

1) Well-suited investors & developers:
The fact that giants are currently financing these studies (Shiseido, Kyocera & L'Oreal) is an amazing indicator as usually shitty studies (more risky, less potential positive output) are mainly financed by public funds (it is a fact). On the other hand, Hairloss has not benefited from a "momentum" such as some tech companies did before having their R&D pipeline financed by private companies. This is a secound positive indicator: hairloss technologies in itself are not benefiting from a speculation factor. So only scientific evidences & success potential are priced in their investment offer. Not a trend premium; a good point for us.

2) A healthy competition:
Three market segments are being covered : Norwood-fucked up (namely, 4-7) and Norwood-shitty (3) and even Norwood-ok (1-2) for all 3 solutions and are potential competitors (even if we can predict L'Oreal as being a well suited actor for people being savagely hit by the sickness at the moment and would'nt invest much money in (1) & (2), or people who just want to modify a stabilized hairline, still a huge market ) . As a result, all these companies are just shitting in their pant to be the first standard of care in the industry and replace the Big 3.

Note: It seems that there are more synergies between (1) Shiseido/Replicel and (2) Kyocera/RIKEN tandems which even have labs in the same street. Some colusion may be on the line. Nice thing for us.

3) The first cellular products developed for one purpose: ending Baldness. A completly different situation than with Rogaine & Finasteride:

Rogaine & Fina had other purpose than curing the Head-Balls-Syndrome (aka bald male pattern) and in the end, they created a market which was dominated by snake-oil crap, hair transplants & shitty wigs. In a way, they oppened the door to Giants like L'Oreal to make the big move: if a pseudo solution like the Big 3 could raise billions in few decades, the right solution would make them rich. The only thing was to wait to the right moment and current R&D development will permit to propose the first process purposely funded to cure baldness. This is a key breakthrough: it's the first time in history of the mankind that an optimal process is being developed for the only purpose of curing (and not having a half solution) the Head-Nuts-Syndrome aka andro alopecia

4) Let be brief: proof of concepts are all done for these 3 solutions. Preclinical done. Phase I Phase II on the move; this is good news. Lot of risk of failure is behind us.

5) Highly ranked specialists working to develop R&D pipeline

Having a Lee Buckle as CEO at RepliCel is a good thing and the company is covered by analyst Douglas Loe who is a good lad, José Cotovio from L'Oreal is quite bullish (he's bald btw) which means a lot , and seing all the names of the Japanese experts, you know our hopes are in good hands, not as in the snake-oil-products period (10 years ago).

All these people would never put their reputation at stake in a shity project; business is like that.


So, on a nutshell: our hopes are backed by relevant success factors this time (INCREDIBLE financial support, great management, experts with strong reputation, succesful proof of concepts & Phase I, and great approaches being either cellular or biologic) . Which is a first time in history of baldness.





I'm sorry that your post is doomed to be attacked by the so called "rational" ppl here. You will hear "What have we got in the past 20 years? Be realistic, nothing gonna save us, take finasteride, we are fxxked". They like spread desparate emotion I am sure some of them are hair transplant shills especially the member with name starts with "Foll".
 

Armando Jose

Senior Member
My Regimen
Reaction score
1,004
as usually shitty studies (more risky, less potential positive output) are mainly financed by public funds (it is a fact).


??? If it is alopecia areata its posible but no public funds in androgenetic alopecia AKA common hair loss.
 

GodisnotBald

Member
Reaction score
10
??? If it is alopecia areata its posible but no public funds in androgenetic alopecia AKA common hair loss.

Dear sir,

I was speaking "from a general point of view" ; seeds project with crapy risk are usually financed via public funds & incubators; more mature projects & / or more "promissing" companies (depending on key people profiles and other tangible factors such as patented technology ouput quality, scientific évidences, good regulatory files, PoC or preclinical results,...) start to attract private companies and their business development department which does not have time to invest in companies which are not worth investing in

And make no mistake, you're not working for the best (L'Oreal and the two Japanese) in one of the sexiest departments in these companeis aka Business Development (buying / investing in other project / partnership / businesses ) if your not a rational genious spoting attracting investment opportunities. Mistakes can be done; here we've got 3 giants with possibly the best experts in the sector. It minimizes risk. A bit like if Bill Gates Waren Buffet and Sorros were investing in 3 different projects aiming to serve a similar problem. You just now this problem will be solved; they developped success patterns optimising positive outputs in every decision they make; together, there is statistically no chance the 3 projects will go nowhere.

In other words, this is not snake-oil crap, this is a world-class sh*t.



A real preventive method is the first step to achieve a posssible cure, till then there is no cure. Why efforts from these companies are not encaminated to it?

Dude, you will notice that "preventing" and "curing" is, for baldness, a similar step. Only time make the dramatic difference as "curing" means stoping the evolution of baldness (and transplanting new hair like L'Oreal plants to do) // preventing means stoping early (before andro alop' destructs your head) with the same product

Anyway, I'm a sceptical person when it comes to health care topics; and right now I'm quite optimistic as facts are totally inedit. It's a bit like when Cuba discovered a vaccin for lung cancer or when allograft were proposed to treat fractures: these 3 projects for hairloss are promissing
 

That Guy

Banned
My Regimen
Reaction score
5,361
So they published the results from their tendon repair therapy which uses fibroblast or some sh*t like that taken from hair follicles.

It works as well.

The power of hair is mighty, indeed.
 

inham123

Established Member
My Regimen
Reaction score
59
Any links, That Guy? This is very good news as it will attract investors and improve the reputation of Replicel.

I hope their skin rejuvenation sh*t works too lol. Only plastic surgery I would want is hair transplants, removing some body hair and skin rejuvenation.
 
Top