The Concept Behind Follica Has Been Known Since The 1950s, Why The Heck Is A Product Taking So Long

nameless

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Several reasons, none of them good.

• Baldness research is seen as a waste of time and resources; the "just shave it, bros" only compound this problem.

• Most men don't care (and many still don't) before the age of the selfie.

• The FDA and other archaic administrations

• People bitching about "ethics" where the words "stem" and "cell" appear together in the same sentence.

People have been trying to cure hair loss for thousands of years.

The reason a cure has not been produced yet is because science is not advanced enough yet to cure the problem.
 

nameless

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No the science is here, it's because of the extreme amount of red tape we have nothing new on the market.

Tsuj is the researcher closest to curing hair loss and even he still has details to work out.

I'm talking about a real cure. I'm not talking about a little hair (that isn't even enough to change the way you look) from Follica. I'm talking about getting back a full head of hair.
 

Distressed

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People have been trying to cure hair loss for thousands of years.

The reason a cure has not been produced yet is because science is not advanced enough yet to cure the problem.
Like Pigeon said, the science is here, but the problem is:

A) Not everyone responds to usual treatment
B) The real effective treatment has to jump through hops of FDA and funding
C) Like I said before, not everyone takes hair loss seriously
D) It's not like we have hundreds of companies trying to solve this like we do for cancer and major illnesses. If that was the case, I'm sure we'd have a cure/be pretty close to one while having actual, reliable treatment that doesn't give out within 5-10 years.
 

kiwipilu

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keep your faith
7447426355.jpg
 

NewUser

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In 2015, the median time to approval for new drugs was just 37 days faster for Japan's PMDA than USA's FDA. For me, that's not breathtaking enough to get excited about. That is unless Shiseido is able to produce good results and get approval sooner than later. That would be awesome.

Science takes as long as it takes imo. There are few to no shortcuts. Yes the science has improved a lot in the last, what, 10 to 15 years? UCLA's announcement that they are able to activate stem cells to grow HF is astounding. I really do think drugs to grow hair are coming and will be the most cost effective solution. I think we can now hope for a drug that induces hair growth in bald scalps, stimulating normal HF growth and without problems like "direction" of growth, issues with angle etc. And with Krox20 and SCF discoveries recently, they will even be able to grow hair with its original color. No more gray hair. Gray hair is also a "death symbol" for some of us. Nobody wants cryptkeeper hair, either.

But it's the technology that is behind and not so much the science. Finally, the science is speeding along at breakneck speed it seems. What we need are some brave engineering wannabes, or some actual biotech engineering technologists to test the limits and push the envelope of the practical and what is already known. Progress in science and technology comes often from doing things differently in unpredictable ways. Angela Christiano is the Orville Wright of hair biologists with her discovery for Jak-STAT signalling and producing what is hoped to be the first legit treatment for AA. We need more Orville Wrights to push the boundaries of science and technology in every area of research.

Lord Kelvin, the President of the Royal Society of England once said, "Heavier than air flying machines are impossible!" But he was proved wrong by the Wright bros who had the courage and stubborn will to test the limits of scientific understanding in their day.
 

vernon

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In 2015, the median time to approval for new drugs was just 37 days faster for Japan's PMDA than USA's FDA. For me, that's not breathtaking enough to get excited about. That is unless Shiseido is able to produce good results and get approval sooner than later. That would be awesome.

Science takes as long as it takes imo. There are few to no shortcuts. Yes the science has improved a lot in the last, what, 10 to 15 years? UCLA's announcement that they are able to activate stem cells to grow HF is astounding. I really do think drugs to grow hair are coming and will be the most cost effective solution. I think we can now hope for a drug that induces hair growth in bald scalps, stimulating normal HF growth and without problems like "direction" of growth, issues with angle etc. And with Krox20 and SCF discoveries recently, they will even be able to grow hair with its original color. No more gray hair. Gray hair is also a "death symbol" for some of us. Nobody wants cryptkeeper hair, either.

But it's the technology that is behind and not so much the science. Finally, the science is speeding along at breakneck speed it seems. What we need are some brave engineering wannabes, or some actual biotech engineering technologists to test the limits and push the envelope of the practical and what is already known. Progress in science and technology comes often from doing things differently in unpredictable ways. Angela Christiano is the Orville Wright of hair biologists with her discovery for Jak-STAT signalling and producing what is hoped to be the first legit treatment for AA. We need more Orville Wrights to push the boundaries of science and technology in every area of research.

Lord Kelvin, the President of the Royal Society of England once said, "Heavier than air flying machines are impossible!" But he was proved wrong by the Wright bros who had the courage and stubborn will to test the limits of scientific understanding in their day.

great post but I dont see that rapid advancement of science, not just in terms of hair loss but generally.

very little problems are actually being solved, when you put wishful thinking, over-exaggerating minor discoveries and the "this may lead to x in x years" and "in 2028 we will have this and this" type of news aside

relying on hypothetical scientific miracles is almost becoming a cult
 

NewUser

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Believe it or not ... There are companies really desperate to bring to the market an effective treatment for male pattern baldness.

Yes there are. I think the problem or hurdle for most startups is risk. Clinical trials are the testing of existing scientific knowledge in search of practical technology. Clinical trials are expensive, and the companies with the deepest pockets are hoarding cash. Big pharma and other industries are currently sitting on mountains (and mountains) of cash that could be invested in research and clinical trials.

Why?
 

pollutionbrain

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I think the only reason that there arent any other treatments for male pattern baldness than propecia and rogaine is because the companies selling those drugs bought the patents for potential treatments/cures and then shelved them. I don´t think this will happen anymore because merck and the company that owns rogaine has lost their monopoly, just look at the generics that have hit the market. It´s probably the lawsuits against merck combined with too many new potential cures that made these guys give up.
 

vernon

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I think the only reason that there arent any other treatments for male pattern baldness than propecia and rogaine is because the companies selling those drugs bought the patents for potential treatments/cures and then shelved them. I don´t think this will happen anymore because merck and the company that owns rogaine has lost their monopoly, just look at the generics that have hit the market. It´s probably the lawsuits against merck combined with too many new potential cures that made these guys give up.

yeah, why make 10 billions when you can make 2.

just stop with that dumb argument already
 

dermrafok

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I think the only reason that there arent any other treatments for male pattern baldness than propecia and rogaine is because the companies selling those drugs bought the patents for potential treatments/cures and then shelved them. I don´t think this will happen anymore because merck and the company that owns rogaine has lost their monopoly, just look at the generics that have hit the market. It´s probably the lawsuits against merck combined with too many new potential cures that made these guys give up.
Yes, there are really many lawsuits against Propecia...

https://topclassactions.com/lawsuit...propecia-bellwether-trials-postponed-to-2017/
 

NewUser

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Investors in many industries value hoarded cash negatively, some as much as 40 cents on the dollar. But with big pharma and software industries, investors value a dollar of savings by anywhere from $1.50 to $2 bux. Why would they hoard this cash and especially if their CEOs believed the economy ahead looks bleak and innovation stagnant for very many years to come? I think it is because they believe something big is around the corner, and they will need the stockpiles of cash to invest. There are a myriad of other things they could be investing in and making more than the piddling savings rates today. I think they are storing up war chests of money for what they perceive as something bigger than doling it out as blue chip dividends and more lucrative divestments.
 

dermrafok

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Honestly, I think you can not tell an exact date randomly, companies are working very hard to bring a product. All of you do not have to worry about when the treatment will be release or what the effectiveness of the product/treatment will be...:)
 

bigentries

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Cuba? Please aware us on all the cuban scientists working on hairloss.
Probably none because there is no knowledge on how to treat it. The science isn't there. Socialized medicine has priorities, but you bet if the "science was there" then the Cuban (or Indian, Chinese, some Caribbean countries) would throw resources into a barely regulated cure that would attract insane amounts of money from medical tourism.
 

abcdefg

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Medicine and science arent the same thing. Medicine is not like any normal science just like a social science is arguably not much real science either.
Someone I know who works at a pharma company said he is looking at research for new male pattern baldness drug. I didnt ask them what it was though. I think in a few years more options will exist, but yes its very very slow. Red tape mostly, but its a lot of things like costs.
 

NewUser

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Probably none because there is no knowledge on how to treat it. The science isn't there. Socialized medicine has priorities, but you bet if the "science was there" then the Cuban (or Indian, Chinese, some Caribbean countries) would throw resources into a barely regulated cure that would attract insane amounts of money from medical tourism.

Cuba, a politically isolated island nation of about 11.5 million people, is already punching above its weight with respect to drug development. You can only do so many things with that few people. They may have world class biotech research facilities, but they just don't have the manpower to manufacture so many items they are short of.

What the war on Androgenetic Alopecia needs is a national foundation to fund and organize research, like the National Alopecia Areata Foundation that funded Angela Christiano's research into Jakinibs. Right now tens of millions of us suffering from Androgenetic Alopecia have no a real central organization to funnel donations for research. TMeanwhile the NAAF looks to have clearly defined goals and meet every two years to assess progress made.

These private startups working on Androgenetic Alopecia are small and secretive, and not much collaboration going on by what we've observed. But they are small and secretive probably due to the fact that a cure or legit treatment for Androgenetic Alopecia will be far, far more lucrative than one for AA affecting a much smaller number of people.

The National Alopecia Areata Foundation conducts research summits every 2 years to review progress and create new directions in its funded and promoted research. The Foundation brings together scientists from all disciplines to get a broad and varied perspective. These summits are part of the Foundation’s main strategic initiative, the Alopecia Areata Treatment Development Program to accelerate progress toward a viable alopecia areata treatment.

I'm guessing the UCLA patents for a drug that activates or blocks the lactate-pyruvate channel in HF stem cell metabolism will be scooped up by some drug company or another. This seems to be the case with "lowest hanging fruit" produced by publicly-funded research(socialism shhh!) in the US before being handed off to private enterprise.
 
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pollutionbrain

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yeah, why make 10 billions when you can make 2.

just stop with that dumb argument already

Whatever, I dont see it as a big conspiracy but as a normal investment of companies that have monopoly. A potential cure is not even close to a real cure.

(Edit: With "cure" I mean a treatment for male pattern baldness which show similar results as finasteride or minoxidil)
 
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nameless

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Since some posters think that the science to cure hair loss is already on the planet, and has been here for awhile, will those people please post what earthly science exists today that could completely cure hair loss for the overwhelming majority of Androgenetic Alopecia patients?

The only potential major cure that I saw get sh*t-canned is RU58841 but the company had a reason to sh*t-can it.
 
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