Thorn Medical claims cure

Pray The Bald Away

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Yes, it's garbage.

First tell "we have 100% success". Second tell "bahamas". Third tell "need to tweak it for female alopecia".

Close this thread.
Female alopecia is different because it tends to lack a stable donor zone sometimes. It makes sense that they would need to tweak the procedure. Perhaps they are looking at taking cells from someone else's scalp and then combining it with the recipient's epithelial cells. I wouldn't completely dismiss them quite yet.
 

GoldenMane

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From what I've read elsewhere, other groups working on hair follicle cloning haven't yet resolved the issue of the extra cellular matrix required to culture the cells in vitro. The issue being cells reverting from hair follicles structures into fibroblasts, and the direction of hair growth is also an issue.
I find it hard to believe that this team secretly perfected a culture technique without publication in dermatology literature, and that they are no offering the treatment in the bahamas with no evidence, photographical or scientific that it even works. I'd love to be proven wrong though...

I still think that whatever the "cure" may be, it will most likely be related to cellular signalling, inducing existing pluripotent cells into differnetiating to the necessary cells required to grow hair. I just don't think it's likely that a service in which stem cells are harvested, cultured (how long would it take to culture even 1000 fibroblasts? that's a genuine question, I don't know!), differentiated and reimplanted.
 

champpy

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Hahaha

I would keep your composure. Who knows if this is legit.

As others have said I think if someone had the cure they'd show tons and tons of pictures showing incredible results. We haven't seen any yet.

Exactly, lets not pee all over ourselves until we see some proof. Any proof. Hell, if i see 25% regrowth im sold
 

Pray The Bald Away

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From what I've read elsewhere, other groups working on hair follicle cloning haven't yet resolved the issue of the extra cellular matrix required to culture the cells in vitro. The issue being cells reverting from hair follicles structures into fibroblasts, and the direction of hair growth is also an issue.
I find it hard to believe that this team secretly perfected a culture technique without publication in dermatology literature, and that they are no offering the treatment in the bahamas with no evidence, photographical or scientific that it even works. I'd love to be proven wrong though...

I still think that whatever the "cure" may be, it will most likely be related to cellular signalling, inducing existing pluripotent cells into differnetiating to the necessary cells required to grow hair. I just don't think it's likely that a service in which stem cells are harvested, cultured (how long would it take to culture even 1000 fibroblasts? that's a genuine question, I don't know!), differentiated and reimplanted.
Cellular signalling will probably be off limits for a while though. It seems like there would be a high risk for cancerous cell proliferation. I'd like to hear from either Malcom Xing or Takashi Tsuji on how they plan to regulate the direction the hair shaft grows. That seems like the part that would be most frustrating.

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And I don't think there are pluripotent stem cells in the scalp. I thought they had to be artificially induced in the lab. Am I wrong?
 

IDW2BB

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I'm getting to the point that I'd just as soon the "cure " would be a transplant. Grow my hair somewhere else, make sure there is 0% I get tumors or cancer, then give me a full head of hair. No altering my cells in my body. No drugs and risk of sides.
This company may be moving in that direction but idk.
 

GoldenMane

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Cellular signalling will probably be off limits for a while though. It seems like there would be a high risk for cancerous cell proliferation. I'd like to hear from either Malcom Xing or Takashi Tsuji on how they plan to regulate the direction the hair shaft grows. That seems like the part that would be most frustrating.

- - - Updated - - -

And I don't think there are pluripotent stem cells in the scalp. I thought they had to be artificially induced in the lab. Am I wrong?

As far as I'm aware, there are stem cells in the scalp, but you're right,, I'm wrong, they aren't pluripotent, but can be induced to be as you mentioned. I'm no expert, but as far as I know they are somewhat differentiated, but not fully, and are capable of forming multiple types of cells within the skin including the necessary hair follicle components. I don't think there's much of a danger of them forming cancerous cells via the wnt pathway targets previously mentioned. It's very unlikely that they could induce adult somatic cells into becoming undifferentiated cancer cells really.

It doesn't really matter though, as far as this announcement is concerned, the idea that they have solved the issues related to hair follicle cloning is very unrealistic, and the idea that they even have the necessary laboratory to take and culture the cells to be induced to form hair follicles is also highly doubtful. A very brief glimmer of hope as usual, but we literally have no reason to believe them, neither evidence nor logic.
 

GoldenMane

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Hair follicle cloning is minimum 10 years away. None of us can wait for that. https://www.youtube.com/watch?v=oKRwlNuDMU0 Eng subtitles are available. If you want to regrow hair here and now, all you've got is hair transplant's, finasteride, dutasteride, minoxidil and spironolacetone if you're brave. This stuff isn't coming by 2018, not by 2020, 2026 at the earliest... If we're lucky. And when it does, it'll be expensive... A flight to Japan, biopsy, then they take the cells to an external lab, culture them (how long does that take?), possibly need to fly back at a later date... And I can promise you it won't be cheap...
 

youngl

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The good thing is, true or fake news's, nowadays we can see that many hair-loss researchers are focusing more on regenerative medicine & technologies ( means regrow I guess). this is a good sign right? true or fake we need more competitors. then we can choose the right one and get our job done.

Comeon hair-loss researchers, this market is yours and huge, also we have lot money, come and get it haha. ( and don't forget proof your "cure" if you want my money lol )
 

slam1523

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Hair follicle cloning is minimum 10 years away. None of us can wait for that. https://www.youtube.com/watch?v=oKRwlNuDMU0 Eng subtitles are available. If you want to regrow hair here and now, all you've got is hair transplant's, finasteride, dutasteride, minoxidil and spironolacetone if you're brave. This stuff isn't coming by 2018, not by 2020, 2026 at the earliest... If we're lucky. And when it does, it'll be expensive... A flight to Japan, biopsy, then they take the cells to an external lab, culture them (how long does that take?), possibly need to fly back at a later date... And I can promise you it won't be cheap...

Thanks bud... What else does your crystal ball tell you?
 

distracted

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The end of balding by 2020 guy seems like he knows his sh*t and is very informed so I trust him with the info he provides.

He was very clearly sarcastic in his article. I don't think he has much faith in this and only reported on it because of the overwhelming amount of messages he got on this.

Damn this holds pretty good promise to be honest. They provide solid evidence in this article of their methods and regrowth.

Lol. I knew there was no way you'd be buying this but I hoped.
 

Pray The Bald Away

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Watch the link, Shiseido say as much themselves, it's 10 years away, not 2.
I don't think the title applied to that part of the video. The ten years estimation was for iPS based hair regeneration. Shiseido doesn't use this technology.
 

Armando Jose

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As far as I'm aware, there are stem cells in the scalp, but you're right,, I'm wrong, they aren't pluripotent, but can be induced to be as you mentioned. I'm no expert, but as far as I know they are somewhat differentiated, but not fully, and are capable of forming multiple types of cells within the skin including the necessary hair follicle components. I don't think there's much of a danger of them forming cancerous cells via the wnt pathway targets previously mentioned. It's very unlikely that they could induce adult somatic cells into becoming undifferentiated cancer cells really.

It doesn't really matter though, as far as this announcement is concerned, the idea that they have solved the issues related to hair follicle cloning is very unrealistic, and the idea that they even have the necessary laboratory to take and culture the cells to be induced to form hair follicles is also highly doubtful. A very brief glimmer of hope as usual, but we literally have no reason to believe them, neither evidence nor logic.


Hair fiber is only suported by a operative pilosebaceous unit. In lab, scientist must make all the components if they want a real cure ,,,,
 

hellouser

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Are they growing hair that is not sensitive to androgens? Becuase otheriwse it wont matter as you will start balding again in 1-3 years

Click on the article link swoop posted, it explains everything.
 
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