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What's the point of increasing your estrogen by overdosing on bica? Do you think it will be less "feminizing"? Because it won't be
High amount of estrogen in your body will act the same no matter if it's from bica or e2 pills
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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High amount of estrogen in your body will act the same no matter if it's from bica or e2 pills
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You will have no protection against any of the feminizing effects that you are meticulously trying to avoid
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Yeah, and because of that I see no reason taking high E, maybe E not at all, because Bica gives you already the E you need...
Am I right!?
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It might give you sufficient amount to regrow hair it might not, but if you have to take 150mg to do so. Than just use e2 imo.
Also if you don't reach female levels of estrogen while in an androgen deprived state you'll increse your chances of
bone mineral density loss and fractures, coronary heart disease, deep vein thrombosis and diabetes.
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See the owner of the site's article on shedding which is excellent. The difficulty with marginal treatments is that they might increase shedding while at the same time being overrun by virulent male pattern baldness hair loss making such treatments not recommended for most people. I think Biestro is probably better as maintenance and for females unless you use lots and lots. MtF's have no choice really but to strap themselves in and ride out the shed since there are better pastures ahead but for guys, these treatments might make things worse. This is why I think starting with Min two percent is recommended over five percent and then one can titrate upwards if no shed or significant shed appears.
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No. You misinterpreted what he is saying, I believe. We/he are saying that Bica, if it works, is simply another form of high estradiol dosing that is perhaps not high enough to cause significant regrowth but maybe it is, but you won't avoid major sides and most MtF's even in an XY context experience far more sides from bica and spironolactone than from estradiol and perhaps more so than CPA and MPA which actually do reduce T without f*****g with receptor sites.
like what's his treatment timeline?
Bluecyclone has never done estrogen and was recently tested in the 80s
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That might work. Theoretically, if the fibrosis theory of baldness is correct, it should at least work for a while. You need to maintain anagen so it might work better than duta but duta doesn't interfere with sexual prowess or fertility.
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This is pretty much concurrent with my experience, if your body easily converts test to E, you probably need to rely mostly on androgen inhibition and blocking to a degree, whatever that is, finasteride, dutasteride, bica, cypro, etc. If not, as it seems to be in my case somewhat, you need to supply exogenous estrogen to fill the gap.
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Safer than what? It's not safer than estogen and it's not safer than spironolactone. It probably has fewer or far fewer daily sides than spironolactone but in the long-run, the two appear to be equally safe for liver, etc. In terms of sides and efficacy as per Dogo, yes we all differ in how we process hormones.
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plus oral min and DR plus something for inflammation.
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I am not certain that person suffers from male pattern baldness.
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Bica is a selective nonsteroidal antiandrogen, while spironolactone is potassium sparing diuretic, and a weak steroidal antiandrogen. Bica is infinitly better and is not harmful for the liver contrary to popular belief.
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That's a million dollar question...lol.
No one knows what estradiol blood level will "guarantee regrowth" for you.
I suspect the estradiol level that starts regrowth for you will be dependent on your genetics, estrogen receptor sensitivity in your hair follicles and other variables that we are currently unaware of. Sadly, for some folks, no amount of E2 will bring back their hair.
Do you know your current estradiol level? If it's currently at the low end of the reference range you could try increasing it into the top end of the reference range. There's no guarantees in any of this but an estradiol level at the high end of the male range would be more beneficial to hair growth than e2 at the lower end of the range.
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I defer to you but I have gone through group discussions with folks on transfeminine sciences who see spironolactone as being either equal to or less damaging compared to bica in the long-run. spironolactone is sort of the whipping boy/girl of MtF meds but usually because it makes you feel weird with really stereotypical effects that males fear such as loss of strength, increased fatigue, loss of libido, interference with working out safely due to diuretic/lack of NaCl, brain fog and on and on but some people tout it and people often switch from CPA or Bica and have better feminization on spironolactone. Remember, Bica and spironolactone do unusual things in that they both occupy receptors and increase overall T.
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Obviously, I continue to believe that regrowth can ultimately be achieved by a brute force estrogen attack and @bridgeburn's E2 levels had to be off the charts as well. We have seen folks using massive duta/bica/cpa/spironolactone but except for bridge and me, very few seem to be pushing extreme E2 levels which might be necessary to break down for me, even decades of fibrosis.
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What you and others are probably thinking of is the "predecessor" to bica, flutamide which known to cause liver damage.