Exploring The Hormonal Route. Hair=life.

Norwoody

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All males in my family have DUPA, meaning of that even donor 'safe' zone is thinning. NW7 is the hair condition by the age of early 20's - mid 20's, all in my family history have.
I think I know what you mean. Probably like Brendan Fraser's fate?
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Pls_NW-1

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Have you thought about taking an intermediate step of something like dutasteride + oral minoxidil before going to the next level?
I seriously want to avoid Minoxidil, and yeah, if I won't start Bicalutamide, I will do Dutasteride. But if i DO start bica, I will continue with finasteride. If I will still be unable to achieve some results, I will put in some O MNX into the mix.
 

mj9

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I want to add something additional to my regimen, but I'm not sure which route to take. What would be a good hormonal drug with minimal feminization side effects that I could add to my regimen for growth? I already apply topical E3.
 

JaneyElizabeth

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View attachment 160998

Am losing it since 4-5 years slowly. It's currently very noticeable, honestly thinking about a VERY short cut.

Currently using only Finasteride, thinking about starting Bicalutamide August/-December.
Dunno if anything will help me at all to get back to baseline /pre puberty. I doubt even estrogen will help me. It surely will grow me some D cups, but doutbfully some hair sprouts lol.

Need advice, doctors are all pretty much useless, besides the endo, trans and andrology doctor, I met.
Why not oral minoxidil at 5mg, twice a day like @bridgeburn. I am thinking about going up to 12.5mg twice a day because it seems to work so well.
 

Pls_NW-1

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Why not oral minoxidil at 5mg, twice a day like @bridgeburn. I am thinking about going up to 12.5mg twice a day because it seems to work so well.
I want to firstly know which medication works, I know Minoxidil will work 100% but I want to rule out some meds, so I wont end up dribking all and hurting my liver. Ykwim?
 

JaneyElizabeth

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I want to add something additional to my regimen, but I'm not sure which route to take. What would be a good hormonal drug with minimal feminization side effects that I could add to my regimen for growth? I already apply topical E3.
Your protocol is interesting. Basically everything but CB and alfatradiol. Are you getting regrowth? I don't think estriol is strong enough and it is unclear how much estrogen topicals can achieve without fairly high systemic levels.
 

JaneyElizabeth

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I want to firstly know which medication works, I know Minoxidil will work 100% but I want to rule out some meds, so I wont end up dribking all and hurting my liver. Ykwim?
Makes sense. I thought you were desperate so at least we have avoided that low feeling. That's a good idea.
 

Norwoody

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Yeah you're really swimming upstream... Again, not to sound like a broken record with you, but it is very good that you at least are starting as early as you can. You may have to do something similar to the Noah dude, hit it hard and then pull out. Maybe try low dosages or a short but heavy cycles, pull out and then try to maintain on dutasteride.
 

JaneyElizabeth

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Yeah you're really swimming upstream... Again, not to sound like a broken record with you, but it is very good that you at least are starting as early as you can. You may have to do something similar to the Noah dude, hit it hard and then pull out. Maybe try low dosages or a short but heavy cycles, pull out and then try to maintain on dutasteride.
Yeah. That's a good point. I lost hair young at 19 but my father still has a full head of hair in his 80's as does my mother.

As bald as PLS's father is, I mean, yikes. Now I get his urgency. I wonder if estradiol could do anything for that big bald scalp. There is virtually no fringe hair.
 

Norwoody

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I mean at the end of the day, my question really is: can we treat feminizing drugs like we do masculinizing ones? That is, can we use multi-faceted HRT at either low doses for a bit longer or heavy doses for a brief period, and hoping we can return to baseline hormonally? We KNOW that we can cycle anabolic steroids this way, and our endogenous T / HPA axis will return to normal afterwards.
 

JaneyElizabeth

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I want to add something additional to my regimen, but I'm not sure which route to take. What would be a good hormonal drug with minimal feminization side effects that I could add to my regimen for growth? I already apply topical E3.
I am looking at all of my meds because otherwise you have sort of max'ed out and you might want to adjust dosages upwards. But I see progesterone and medroxyprogesterone both of which might help hair but they also lower testosterone, which is how they work. Anything else and you would just be feeding breast growth. Bica raises E2 but it allows for fairly high T levels. I think that's why Almas touts it.
 

mj9

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Your protocol is interesting. Basically everything but CB and alfatradiol. Are you getting regrowth? I don't think estriol is strong enough and it is unclear how much estrogen topicals can achieve without fairly high systemic levels.
My hair feel different, but no cosmetic difference just yet. I feel like I've got some regrowth, but I can't see it on photos yet.
Are you recommending I add CB and alfatradiol.
I've got E2 but I've not used it yet.
 

JaneyElizabeth

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I mean at the end of the day, my question really is: can we treat feminizing drugs like we do masculinizing ones? That is, can we use multi-faceted HRT at either low doses for a bit longer or heavy doses for a brief period, and hoping we can return to baseline hormonally? We KNOW that we can cycle anabolic steroids this way, and our endogenous T / HPA axis will return to normal afterwards.
Marky's the one to ask. I think he is cycling HRT and he definitely has all of his hair and it looks like male hair.
 

JaneyElizabeth

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My hair feel different, but no cosmetic difference just yet. I feel like I've got some regrowth, but I can't see it on photos yet.
Are you recommending I add CB and alfatradiol.
I've got E2 but I've not used it yet.
I am not recommending either one of them but you seemed to be fishing for ideas. Alfatradiol might really only work well for cis-females. I have never seen any impressive pics for any of these, nor Ru really but maybe they are out there but not posting.

The hesitancy I have about recommending E2 to you is that the more that you use, the better it works, apparently and for truly great results you might end up at cis-female adult estrogen targets. Oral min is a bit like this perhaps also.

So I saw a little something when I first used OTC E2 and E3 but eh, it wasn't worth the hassle and cost really. The other thing is that I did have significant body feminization even when the hair part wasn't working. This makes me think that there is a reason why males using HRT for hair loss isn't a thing. I think that you have to become chemically female for above the neck results and that can take a fair amount of time while all the time you are exposed to breast growth. Now I don't think breast growth is as permanent as they say says the person with D cups. Even if I stopped HRT and used raloxi, it's probably too late but I became more and more okay with that. About 2 years ago, I was up to a B or a C and nowhere close to my hair goals so my decision was that I knew this could and would work so onward I continue.

Once I went to unlimited amounts of estradiol and added oral min at 12.5mg, the regrowth became thrilling, it was coming in so fast and it finally was looking good worn long not like a hobo like six years back. I can still see the remnants of what used to be mullet-y hair but it is relaxing and looking nicer and nicer long. I haven't posted in a while because maybe it is more dramatic sometimes to wait. So so close to my life-time dream since the age of 20 which was to have back my 16 year old hair again.
 

JaneyElizabeth

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Ticken,
If you are out there, have you tried Alfatradiol? I saw a study that I should have kept the link for, that said that it was effective for females when used with minoxidil. I don't think it does much for guys in isolation. I am not sure that it is synergistic either. If more meds were synergistic, maybe this wouldn't be so hard!
 

JaneyElizabeth

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So this is a thread from an acquaintance of mine with great all around knowledge of HRT. I am not thrilled by this because she was using parenteral estradiol and now blames it for several blood clots. The thinking has been that mostly pills cause clotting issues and liver issues but she also was maintaining pregnancy levels of estradiol for six years. I reach a year in June some time.

@bridgeburn was also taking a fair amount of synthetic stuff and maybe somebody can estimate his E2 levels but my guess is always above 300 pg/ml and often much closer to 1,000 pg/ml. He did not test which could further increase the risk. I am going to test tomorrow and I am curious to see what I hit because I ran out of estradiol for a couple of days this week and then my PA asked me to test before renewing my patches which have worked so great with the estrogel. I am out of Estrogel for the first time in a year and I am debating whether to buy ten more tubs, lol, I need tubs, but tubes rather, but cha-ching at some point. I have spent scandalous amounts on Estrogel and that's at the one third of the price off-shore prices.

Because I can always get more Estrogel, cutting me off from patches does little but I don't want to take on more risk than necessary to reach my goals. On the other hand, because hair restoration often seems to be dependent on reaching thresholds, I was tired of slow titration for five years that hadn't gone very far. Since then Zoom! Two patches plus 1.25 Premarin plus unlimited Estrogel plus 12.5mg daily of oral min and Zoom, Zoom! YMMV.


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JaneyElizabeth

just now

Sigh. So six years. I am going to assume that maintaining first trimester levels ~2,600 for ten months is no different from being pregnant but I guess you were pregnant for six years running.
I am doing hair research and it is going stunningly well but I don't intend to stay up here forever.
Was there some particular effect you were seeking?
I am very sorry. I hope you have a fast recovery. There's a reason some times why people are absolute experts so maybe Goddess wanted you to pull back a little. We can all get obsessive about the power we feel over our bodies via HRT. For me, so far, everything has worked uncannily and I struggle with how much of that is luck and how much has to do with my accumulation of research and my willingness to at least bear some extra risk.
Goddess bless,
Janey
 
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