Exploring The Hormonal Route. Hair=life.

JaneyElizabeth

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One theme admitted by Bridgeburn is significant gyno and then breast growth and that comes up again and again as well as the questions about "dead dick syndrome" and it's a bit repetitive for re-posting.
 

JaneyElizabeth

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Georgie said:


I have a full bottle of spironolactone. Wonder if I should experiment with 50mg to see if it stops the bloating. That’s one fucked regimen though. spironolactone, RU, dutas, Diane, 5mg minoxidil oral, stemox... sh*t. Maybe I should just cut back the dose :/
probably would but isn't spironolactone dangerous for you? I think you would get good results with cypro but Im worried it could possibly worsen your depression.
Georgie said:


I am praying that your regimen does end up giving you a full, lasting head of hair.
Ive been on my new dose of 4mg E for only a little over 2 weeks now. I think ive seen boost in improvement after increasing E but you could be right that most of this might be initial minoxidil regrowth.. I habent used oral minoxidil too long, about 2 months i think.
but we'll see! I know I wil get my hair back no matter what!!! If i lose hair again I will make ecerything stronger and stronger and I will go as far as i have to possibly go! regrowth is my mission in life, If I have to take cypro + 8mg E + 20mg oral minoxidil + setipripant+ dermarolling+ 1mg dutasteride+ topical minoxidil with topical finasteride+ topical diane 35.. then I will!!!!
 

JaneyElizabeth

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Sadly, no, Georgie:






@bridgeburn this is an article produced by folliclethought which details some of the promising treatments to come in the near-ish future. Closest one to actually being available seems to be Brotzu, and apparently replicel are aiming for the end of the year. I personally think that Histogen, RiverTown Therapeutics (the trials regrew all hair and also showed regeneration of lost pigment), Brotzu and possibly Aclaris look most promising. I’m frothing to get my hands on some of these things.
http://www.folliclethought.com/tag/brotzu-lotion/

Some things to maybe look forward to if you don’t end up getting the results you want anyway.

Here are the results from RiverTown Therapeutics, Brotzu (the little girl), Histogen



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JaneyElizabeth

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Bridgeburn Dosing Info:

I am about 1/30th through the thread speed-reading I have read all of this before. He still has no active followers emulating him and except for "is my hair alright?" pics, nobody is posting pics yet at all.






Jesse Navarro said:


Thanks again Bridgeburn. Sorry to disturb you again, but how many pumps do you take? I'm using a 0,6 estradiol gel.
Jesse Navarro said:


I left my laziness behind and did a research. Guess ill use two pumps
my gel doesn't have a pump measurement system. basically like a tube of toothpaste i squeeze it out onto a measurement stick tool. My regimen with the gel has changed a few times so hard to answer how much i take. currently, im not using gel just 4mg of estrofem pills. but before ive used:

with 50mg cypro i used 1.5mg topical E
and then 25mg cypro and 2.25mg topical E
and then no cypro and 3mg topical E
and then a 2mg E pill and 1.5mg topical E
and then for a couple weeks i used 1 diane35 pill and 1.5mg topical E
 

JaneyElizabeth

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itchymadscalp said:


I would love to have those results ... after 4 months on CPA (25mg) Estradiol (4mg) still no regrowth at all, it's even worse.
how do you take the estradiol?




youth is more valuable than gender.
an enemy of hair is an enemy of mine.



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bridgeburn


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itchymadscalp said:


@bridgeburn : orally (4mg) and topically (estrogel, something as big as my thumb, so not so big :D ).
oral Valerate? or hemihydrate?




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bridgeburn


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itchymadscalp said:


@bridgeburn : valerate, because it has a long half life. Same with estrogel, longer half life.
Ive heard bad things about oral valerate. that it could mess up your E:1/E:2 ratios. in my opinion buccall or sublaball methods is better.
 

JaneyElizabeth

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bridgeburn said:


you should probably stop the Bi-estro since it contains a weaker estrogen that competes for receptor binding
In that case shouldn't I stop even Estrogel since it may compete with Daro for receptor binding? Also the days I used the unheated Daro, I didn't use Estrogel until like the fourth day.






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bridgeburn


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SpaceInvader said:


In that case shouldn't I stop even Estrogel since it may compete with Daro for receptor binding? Also the days I used the unheated Daro, I didn't use Estrogel until like the fourth day.
Daro attaches to androgen receptor not the estrogen receptor. you should use daro and estrogel but never estriol.
 

JaneyElizabeth

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It appears that DHT is remarkably resilient and can synthesize itself for the Duta-not needed folks which I was for a while:

Jesse Navarro said:


What do you guys think about the correlation between low testosterone and hair loss? You think it only affects body hair ou it could harm head hair?
It depends on someones levels of other enzymes throughout the body, the amount of body fat and the amount of aromatase. T can really go both ways, turn into either Dht or E. hopefully its E by the time it gets to the scalp but the problem is that our scalp is a source of 5ar. its a very local problem. So in theory even a small amount of T which makes it to the scalp could turn to Dht and cause high Dht in the scalp. but of course if your lower T very extremely, then you also lower the frequency of instances of T reaching the scalp and the amount of Dht cause maybe there will be less T reaching the scalp than the amount of 5ar in the scalp. dutasteride reduces plasma 5ar by 94% but I fear that much of the 6% left over is in our follicles.
 

JaneyElizabeth

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I don't think that the notion of med-dependent hair is consistent with the prevailing theory of baldness but it might be that fibrosis and calcification can occur immediately in some. Terminal hair should be terminal hair but Bridge also mentions that Min might have hormonal effects too:






hello everyone, a few things have been on my mind. I am wondering how much of this is from the oral minoxidil, my hair is really dense and I am worried that someday i may get synchronized sheds or minoxidil dependence. I know that the minoxidil and the estradiol are both having effects, its kinda weird and cool how i get more body hair on some places for awhile until the estrogen catches up, like right now my arm is hairier because of minoxidil but recently I've been losing hair specifically on my hands, my upper arms are getting fuzzy but my leg hair is falling out. Ive been taking the 10mg only one time per day but its still a high dose and having effect despite its short half life. I know that minoxidil decreases collagen production so I don't think that I want to use it forever if possible.
I realize also that there are trans mtf's on full trans regimens who although get dramatic regrowth and improvement still have much trouble with the problem areas like the temples! I'm wondering if i will need to go stronger, it seems my temples are narrowing in towards the center but still the center is the slowest to improve and most stubborn, it looks better up close but still looks bare from a distance and it is bothering me.

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I know i've improved alot and should be grateful but I want more and more and I'm hoping most of it is not because of the initial minoxidil growth. So,
I will be reducing the amount of oral minoxidil to 10mg every other day which I'm nervous about but I'm going on a stronger antiandrogen regimen today. I don't give a f*** about sides anymore, my dick still works that's all that matters, I want my goddamn youth back!
I'm restarting cypro 50mg everyday, i will use the rest of the 104 pills I have left. I will start using topical estrogel again at 2.25mg along with 2mg buccal estrofem, I'm still on .5mg dutasteride everyday. also I will be using Nizoral 2%, I don't know if it will help but If I'm going to wash my hair at all I want to at least wash it with something that might help it and won't hurt and i think keto shampoo has the most science behind it as far as shampoos go. I dont have a schedule for nizoral, just whenever i feel like washing my hair.
 

Isneezedsohard

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Topical E is the muthafuckin shiznit, it's dialing my hair back at record pace from the brink of terminal hairloss to abundant regrowth.

Topical E along with using a mild anti androgenic supplement (red reishi) alone is basically grabbing my hairloss by the dick and shoving it up its own ***. I'm very impressed so far.

I still don't have any "gyno", yes I'm not really lean, but I'm also not fat, nor in any threat of being so, but out of shape is another matter which I need to make contingencies for so that I can begin working out once more.
this phrasing is amazing
 

JaneyElizabeth

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Poor Georgie. Nothing works for her in the longer-run and she has tried all but literally all treatments known to womankind and mankind:






bridgeburn said:


hello everyone, a few things have been on my mind. I am wondering how much of this is from the oral minoxidil, my hair is really dense and I am worried that someday i may get synchronized sheds or minoxidil dependence. I know that the minoxidil and the estradiol are both having effects, its kinda weird and cool how i get more body hair on some places for awhile until the estrogen catches up, like right now my arm is hairier because of minoxidil but recently I've been losing hair specifically on my hands, my upper arms are getting fuzzy but my leg hair is falling out. Ive been taking the 10mg only one time per day but its still a high dose and having effect despite its short half life. I know that minoxidil decreases collagen production so I don't think that I want to use it forever if possible.
I realize also that there are trans mtf's on full trans regimens who although get dramatic regrowth and improvement still have much trouble with the problem areas like the temples! I'm wondering if i will need to go stronger, it seems my temples are narrowing in towards the center but still the center is the slowest to improve and most stubborn, it looks better up close but still looks bare from a distance and it is bothering me.

View attachment 79174

I know i've improved alot and should be grateful but I want more and more and I'm hoping most of it is not because of the initial minoxidil growth. So,
I will be reducing the amount of oral minoxidil to 10mg every other day which I'm nervous about but I'm going on a stronger antiandrogen regimen today. I don't give a f*** about sides anymore, my dick still works that's all that matters, I want my goddamn youth back!
I'm restarting cypro 50mg everyday, i will use the rest of the 104 pills I have left. I will start using topical estrogel again at 2.25mg along with 2mg buccal estrofem, I'm still on .5mg dutasteride everyday. also I will be using Nizoral 2%, I don't know if it will help but If I'm going to wash my hair at all I want to at least wash it with something that might help it and won't hurt and i think keto shampoo has the most science behind it as far as shampoos go.

Click to expand...
I don’t want to scare you, but I got amazing regrowth in the non-androgen affected areas at first too which has no lasted, and I do indeed have synchronised growth. It’s heart breaking. I can say for me that diane35 never helped, but since you’re a man and you say you don’t care about the sides, it’s something that you could try if you wanted full mtf trans style HRT. Otherwise you would have to take 4mg estradiol twice daily with 100mg progesterone which is also a full blown trans regimen. I’d also like to say that for me, CPA and spironolactone have been ineffective, and daily 0.5mg + Diane seems to be doing diddly squat. 3 weeks on darolutamide and sh*t ain’t looking any better. So far the only thing to regrow my hair HEAPS Initislly was minoxidil. I’ll also point out that, as it’s effectiveness wears off each time during the “recession” part of the synchronisation period, my legs hairs stop growing, then my arms, then facial hair. The only new hairs I have growing out the top of my head are miniturised at this point. My hairline is receding fast. All this despite all my hardcore treatments. I think minoxidil gives false hope initially. Now I have none. Seems to work really well for some people, and honestly I’ve never heard of the kind of bizarre whole body hair growth synchronisation thing with anyone else (mind you, my whole body hair was affected by low estrogen/Androgenetic Alopecia). Now I’m stuck because if I come off, I potentially have irreversible loss without hope of regrowth, and being on it, I only get regrowth for like 3months out of th year which slowly dissipates over the next 6-8 months.






Georgie said:


It’s actually banned in a lot of countries because it causes strokes and clots.
i heard it causes that not just for being stronger but because of the way it is metabolised by the liver.
Georgie said:


taking 8mg of estradiol is a lot more haha. I give very little fucks. I’m willing to do it myself.
try rubbing progesterone cream/gel on your scalp and face too. since it competively binds to 5ar. both e and p reduce dht.

Marky makes his first appearance here. I haven't seen him in a while either.
 

JaneyElizabeth

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From page 20 to 30, it's all pretty much Georgie posting. She knows about everything and can already say what won't work for her. It's actually effective in terms of Bridge having a literary foil of sorts but sigh, it's a bit whiney too.
 

Ticken

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Poor Georgie. Nothing works for her in the longer-run and she has tried all but literally all treatments known to womankind and mankind.
I don’t want to scare you, but I got amazing regrowth in the non-androgen affected areas at first too which has no lasted, and I do indeed have synchronised growth. It’s heart breaking. I can say for me that diane35 never helped, but since you’re a man and you say you don’t care about the sides, it’s something that you could try if you wanted full mtf trans style HRT. Otherwise you would have to take 4mg estradiol twice daily with 100mg progesterone which is also a full blown trans regimen. I’d also like to say that for me, CPA and spironolactone have been ineffective, and daily 0.5mg + Diane seems to be doing diddly squat. 3 weeks on darolutamide and sh*t ain’t looking any better. So far the only thing to regrow my hair HEAPS Initislly was minoxidil. I’ll also point out that, as it’s effectiveness wears off each time during the “recession” part of the synchronisation period, my legs hairs stop growing, then my arms, then facial hair. The only new hairs I have growing out the top of my head are miniturised at this point. My hairline is receding fast. All this despite all my hardcore treatments. I think minoxidil gives false hope initially. Now I have none. Seems to work really well for some people, and honestly I’ve never heard of the kind of bizarre whole body hair growth synchronisation thing with anyone else (mind you, my whole body hair was affected by low estrogen/Androgenetic Alopecia). Now I’m stuck because if I come off, I potentially have irreversible loss without hope of regrowth, and being on it, I only get regrowth for like 3months out of th year which slowly dissipates over the next 6-8 months.

I wonder where Georgie is now and if she ever did find a treatment that worked for her.
Do you recall if she ever tried applying estradiol directly to her scalp?
 

Pls_NW-1

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I wonder where Georgie is now and if she ever did find a treatment that worked for her.
Do you recall if she ever tried applying estradiol directly to her scalp?
Hasn't she said that her baseline endocrine system was like... broken!? Her ovaries didnt work as they should or smt like that, when I remember it correctly.
Poor girl.
 

Pls_NW-1

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Did the drugs the author took feminize him?

I ask myself this question
Yes! Very much. Testosterone production near to zero, never will be the same, testicles athropied.

Tho I would say he looks like a male, but more like a teenager, thats amazing tbh
 

MrSnow

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Yes! Very much. Testosterone production near to zero, never will be the same, testicles athropied.

Tho I would say he looks like a male, but more like a teenager, thats amazing tbh
but yet even with everything he takes, I don't feel like he's becoming a woman do I?
 

JaneyElizabeth

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I wonder where Georgie is now and if she ever did find a treatment that worked for her.
Do you recall if she ever tried applying estradiol directly to her scalp?
Well, I am trying to go through it all still as she posts as much as Bridge but another female has asked me for help for a similar reason and it's actually harder to articulate a treatment for females.
 
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