I have a question don't think or know if its been answered on here or not
The lotion--does it improve upon someone having good results on already existing medications?
Like if someone is on minoxidil and or finasteride for years with decent results but not perfect--can the lotion improve upon those results?
That's a very specific question, I can give my PoV but I can't be sure since the lotion is not on the market.
Dr. Brotzu repeatedly say that this treatment should be efficient for those who have a not-compromised situation. On IESON we debated for pages about the concept "dead follicule", and we came to say that it is only an experimental evidence, but there is no theory in tricology/dermatology about that, not even a definition. Let's suppose it is right. The lotion should act on the follicule in 3 ways, DGLA, Equol, Carnitine all carried by cathionic liposomes.
There is no actual cure in the world which does even one thing of those components in the same exact way. Finasteride acts totally different from Equol. minoxidil acts only on the perycite as a vasodilator (Brotzu was the first to explain its mechanism, unknown in tricology), while PGE1 is a strong vasodilator. Carnitine helps cellular metabolism. All is carried by cathionic liposomes, which is demonstrated to penetrate the skin and carries all of them in the deepest part of the follicule.
If we suppose right the concept of "still-living follicule", DGLA converts to PGE1 thanks to Carnitine and other molecules in the cells; PGE1 then re-establish the microcirculation and heals the non-compromised follicule; Equol binds the DHT and it makes un-bindable to the receptor, preventing further damages.
No cure actually on the market does even one of what those 4 components do, or at least, not in the same way. No cure actually repairs the damage at the level of microcirculations, which is for Brotzu the very main symptom that causes hairs to fall. Finasteride blocks DHT, but does not heal the follicule; minoxidil "drugs" the follicule stimulating the pericyte to "pump" more blood but it does not act on the DHT and not in the exact zone in which is required.
Further effects should be discovered by ourselves...