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Dehydroepiandrosterone sulfate (DEA-SO4) is an androgen, a male sex hormone that is present in the blood of both men and women
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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technically they can say that because the prostate is part of the body but that doesn't mean they should. Eunuchs had significant feminizing effects.
yes, the scalp is kinda like the prostate, producing 5ar onsite which fucks itself.
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Dehydroepiandrosterone sulfate (DEAS) is an androgenic hormone produced in men and women in the adrenal cortex as a result of cholesterol esterification. DEAS has a weak androgenic effect, however, during its metabolism, testosterone and dihydrotestosterone are formed in the peripheral tissues.
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The hormone is an indicator of the nature of the formation of androgens: its high content indicates the adrenal origin
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is it overgrown with hair? no one has yet canceled the adrenal glands, they produce the most important androgen dihydroepiandrosterone 95%
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Androgens are male sex hormones that stimulate the growth, development and functioning of the male reproductive system. All androgens synthesized in the body of a man are divided into adrenal and testicular. Adrenal androgens include dehydro-epiandrosterone (DHEA), dehydroepiandrosterone-sulfate (DHEA-S) and and-rostenedione.
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Dehydroepiandrosterone or DHEA - is a hormone with androgenic activity. DHEA is responsible for the development of secondary sexual characteristics, maintaining sexual function, and also has anabolic effects. 90% of the hormone is formed in the adrenal cortex, the remaining 10% is synthesized in men in the testes, in women in the ovaries.
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In addition to its affinity for the androgen receptor, DHEA has also been found to bind to and activate the ERα and ERβ estrogen receptors with Ki values of 1.1 μM and 0.5 μM, respectively, and EC50 values of >1 μM and 200 nM, respectively. Though it was found to be a partial agonist of the ERα with a maximal efficacy of 30–70%, the concentrations required for this degree of activation make it unlikely that the activity of DHEA at this receptor is physiologically meaningful. Remarkably however, DHEA acts as a full agonist of the ERβ with a maximal response similar to or actually slightly greater than that of estradiol, and its levels in circulation and local tissues in the human body are high enough to activate the receptor to the same degree as that seen with circulating estradiol levels at somewhat higher than their maximal, non-ovulatory concentrations; indeed, when combined with estradiol with both at levels equivalent to those of their physiological concentrations, overall activation of the ERβ was doubled. As such, it has been proposed that DHEA may be an important and potentially major endogenous estrogen in the body.[10][19]
with that said it can still turn into Dht so block the hell out of it
with that said it can still turn into Dht so block the hell out of it
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If your hair loss is auto immune related or from inflammation it may help, though you can't use indefinitely and you have to cycle (couple weeks on, couple weeks off) to prevent skin thinning.
so does it make things worse?
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Shouldn't make things worse as long as you don't use too frequently. It just likely won't lead to regrowth unless there's a specific immune reaction that it would be modulating or possibly could help something like seb derm. But even then it's a pretty weak corticosteroid.
so what you think retinoic acid? should i use it on my temples?
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it is androgen, not estrogen, otherwise it would be called dihydroepiestrosterone
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it’s only possible, through some metabolism, it can turn into estrogen but not in our case balding
How was his hair guys? I wasn't here for 2 days. Was there cosmetic regrowth or some toyish hair?
Wtf! I'm fuckin tired of this pill. I see to not retain much from my classes these days.
Shall 50 mg Bica help me?
Noah, I'm feeling miserable atm. If FFS I hop on 50mg Bicalutamide (or 75 or 100 from) I'm still not assured of results. Moreover, I'm looking way worse without muscles. Also lost lots of weight on spironolactone. Raloxifene - from all f*****g - 13 brands is out of stock in my country. Seems like they have banned it.