Gadgetine

Exploring The Hormonal Route. Hair=life.

sg2000

Experienced Member
My Regimen
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290
im not going to use progesterone at all since im using already dutasteride to reduce 5 aloha reductase and btw she prescribed me 0.5% prog 3 times a week so its usless imo
 
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Adri23

Senior Member
My Regimen
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2,447
I thought you were self-medicating it... Wtf dude, just listen to your Derm next time and not some fkin randos on a godforsaken forum.View attachment 189993
This is why most of the people are just not suited for DIYing. IMO, if you want to successfully self-medicate, its a mandatory to know at least basics of anatomy, pharmacokinetics, pharmacodynamics and main receptor pathways, otherwise you're just relying on intuition and others opinions. I mean, intuition is good and all, but it's purely based on your knowledge about this world. And if you apply it to matters that you dont know the concept of, you're basically bulding a skyscraper on the foundation of a pit toilet.
+1. Im using all this cause I did a genetic test and I have all kind of f*****g sh*t mutations. Poor cyp19 so I have no aromatization, moderate to high activity of 5ar1 and 5ar2, that is why even with low T my dht is unmanageable without high amounts of dutasteride to control the 5ar1, high angiotensin 2 activity so my circulation sucks, tendency to low IGF-1, Col1a1 moderately reduced bad sulfotransferanse, ptgfr-2 and ptgfr-3 mutations. Basically my genetic suck ***, without e2, high dosage dutasteride, minoxidil with tret + oral min and some supplement for collagen synthesis, antioxidants and arginine for better vasodilation I prob wouldnt have hair today and prob would have wrinkles at my age (that is one of the reasons I was prematurely aging, but I managed to recover thanks to everything im doing).

NO f*****g doubt why my dht was still at 59 ng/dl even with 0.5 mg dutasteride daily pre hrt. What would I expect with 0 aromatization, and moderately to high activity on 5ar1 and 5ar2... I literally couldnt battle my genetic with just dutasteride basically impossible. Way cheaper to use e2 + 1 mg dutasteride at least. Otherwise I would have to use 2.5 mg dutas which is hella expensive and even that wouldnt secure anything since 0 aromatization is also bad
 
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coco_304

Established Member
My Regimen
Reaction score
57
+1. Im using all this cause I did a genetic test and I have all kind of f*****g sh*t mutations. Poor cyp19 so I have no aromatization, moderate to high activity of 5ar1 and 5ar2, that is why even with low T my dht is unmanageable without high amounts of dutasteride to control the 5ar1, high angiotensin 2 activity so my circulation sucks, tendency to low IGF-1, Col1a1 moderately reduced bad sulfotransferanse, ptgfr-2 and ptgfr-3 mutations. Basically my genetic suck ***, without e2, high dosage dutasteride, minoxidil with tret + oral min and some supplement for collagen synthesis, antioxidants and arginine for better vasodilation I prob wouldnt have hair today and prob would have wrinkles at my age (that is one of the reasons I was prematurely aging, but I managed to recover thanks to everything im doing).

NO f*****g doubt why my dht was still at 59 ng/dl even with 0.5 mg dutasteride daily pre hrt. What would I expect with 0 aromatization, and moderately to high activity on 5ar1 and 5ar2... I literally couldnt battle my genetic with just dutasteride basically impossible. Way cheaper to use e2 + 1 mg dutasteride at least. Otherwise I would have to use 2.5 mg dutas which is hella expensive and even that wouldnt secure anything since 0 aromatization is also bad
Are you man or female?
 

Adri23

Senior Member
My Regimen
Reaction score
2,447
Are you man or female?
Born male now male with female hormonal panel. There was no reason to keep myself T dominant. It would've been impossible to maintain my hair that way. It is hard to maintain even on hrt I cant imagine how bad it would be by now if I didnt start hrt
 

coco_304

Established Member
My Regimen
Reaction score
57
Born male now male with female hormonal panel. There was no reason to keep myself T dominant. It would've been impossible to maintain my hair that way. It is hard to maintain even on hrt I cant imagine how bad it would be by now if I didnt start hrt
Where do buy all your staff?
 

Adri23

Senior Member
My Regimen
Reaction score
2,447
Where do buy all your staff?
dutasteride, bica and minoxidil in my country. For Estradiol injections hrt caffe is your best bet. Everything I take can be bought there but it gets way more expensive due to shipping cost + bitcoin fees, only real cheap and worth product is estradiol injections, so if you can get the rest in your own country it would be way cheaper
 
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coco_304

Established Member
My Regimen
Reaction score
57
+1. Im using all this cause I did a genetic test and I have all kind of f*****g sh*t mutations. Poor cyp19 so I have no aromatization, moderate to high activity of 5ar1 and 5ar2, that is why even with low T my dht is unmanageable without high amounts of dutasteride to control the 5ar1, high angiotensin 2 activity so my circulation sucks, tendency to low IGF-1, Col1a1 moderately reduced bad sulfotransferanse, ptgfr-2 and ptgfr-3 mutations. Basically my genetic suck ***, without e2, high dosage dutasteride, minoxidil with tret + oral min and some supplement for collagen synthesis, antioxidants and arginine for better vasodilation I prob wouldnt have hair today and prob would have wrinkles at my age (that is one of the reasons I was prematurely aging, but I managed to recover thanks to everything im doing).

NO f*****g doubt why my dht was still at 59 ng/dl even with 0.5 mg dutasteride daily pre hrt. What would I expect with 0 aromatization, and moderately to high activity on 5ar1 and 5ar2... I literally couldnt battle my genetic with just dutasteride basically impossible. Way cheaper to use e2 + 1 mg dutasteride at least. Otherwise I would have to use 2.5 mg dutas which is hella expensive and even that wouldnt secure anything since 0 aromatization is also bad
How can i do this check..
 

Adri23

Senior Member
My Regimen
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2,447
How can i do this check..
You can try to search on the web for reliable ones. They are kind of helpful but i dont think it is worth the money. I'd first recommend a biopsy which is prob cheaper and will tell you what kind of Alopecia you have. If it is Androgenetic Alopecia, try dutasteride if it doesnt work because your Androgenetic Alopecia is super aggressive(most of the time ppl that start balding from 15 to 20) you wont have a chance with standard male regimen and you will have to do estradiol + dutasteride at 1 mg at minimum to further reduce the adrenal conversion to DHT + an antiandrogen (not to high dosages if you use moderately high dose of dutasteride + castrated T levels) to block the receptor. Basically start balding at light speed between 15 to 25 yo with Androgenetic Alopecia diagnose means you are allergic to androgen(unironically talking, it leads to metabolic diseases as well)
 

coco_304

Established Member
My Regimen
Reaction score
57
You can try to search on the web for reliable ones. They are kind of helpful but i dont think it is worth the money. I'd first recommend a biopsy which is prob cheaper and will tell you what kind of Alopecia you have. If it is Androgenetic Alopecia, try dutasteride if it doesnt work because your Androgenetic Alopecia is super aggressive(most of the time ppl that start balding from 15 to 20) you wont have a chance with standard male regimen and you will have to do estradiol + dutasteride at 1 mg at minimum to further reduce the adrenal conversion to DHT + an antiandrogen (not to high dosages if you use moderately high dose of dutasteride + castrated T levels) to block the receptor. Basically start balding at light speed between 15 to 25 yo with Androgenetic Alopecia diagnose means you are allergic to androgen(unironically talking, it leads to metabolic diseases as well)
Tank you.
 

SnortingFinasteride

Established Member
My Regimen
Reaction score
163
@BeardCombover do you think 0.3 ml(12 mg every 10 days) is enough to suppress T or am i just6 blasting E and cause more problems? 40mg-ml
Bro we already told you yes, your dose is sufficient to keep your T suppressed

As for blasting E and causing problems, well that EEn dose will probably yield levels of e 500 pg/ml at the lowest point. So watchout for blood clots
 
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