Gadgetine

Exploring The Hormonal Route. Hair=life.

xarco

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@Adri23
I also live in Spain and its impossible to get a DHT via LCMS bloodtest. There are a lot of chances of your dht levels not being true.

Other things you can do is test other hormones to make ratios and knowing if your dutasteride is actually working (AdiolG, 4-And, 17-cetoesteroids…). In my case I have hight DHT with 1.5 dutasteride but very low AdiolG.
 

GRme11

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@Adri23
I also live in Spain and its impossible to get a DHT via LCMS bloodtest. There are a lot of chances of your dht levels not being true.

Other things you can do is test other hormones to make ratios and knowing if your dutasteride is actually working (AdiolG, 4-And, 17-cetoesteroids…). In my case I have hight DHT with 1.5 dutasteride but very low AdiolG.

@Adri23 He is already checking all these and he knows. Good call either way. How’s your hair with high DHT, but low adiol? Adiol reflects 5ar activity in tissues. I hope your hair is fine.

 

Adri23

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@Adri23
I also live in Spain and its impossible to get a DHT via LCMS bloodtest. There are a lot of chances of your dht levels not being true.
Which part of spain?
Other things you can do is test other hormones to make ratios and knowing if your dutasteride is actually working (AdiolG, 4-And, 17-cetoesteroids…). In my case I have hight DHT with 1.5 dutasteride but very low AdiolG.

My last blood test looks like this:

Total Testosterone: 25 ng/dl
Free T: 0.21ng/dl (0.83%)
DHT: 18.12 ng/dl
Estradiol: 389.4 pg/ml
Free Estradiol: 6.75 pg/ml (1.73%)
Estrone: 163.3 pg/ml
LH & FSH: Near 0
3 androstanediol glucoronide: 8 ng/dl
Androstenedione: 1.03 ng/ml
DHEA-S: 199 μg/dL
DHEA: 3.01 ng/ml

I:ll get a new test result next friday. The thing is I had lower DHT levels in the same lab a year ago. I am also seeing hair thinning on temples and under trichoscope
 

sg2000

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@Adri23
I also live in Spain and its impossible to get a DHT via LCMS bloodtest. There are a lot of chances of your dht levels not being true.

Other things you can do is test other hormones to make ratios and knowing if your dutasteride is actually working (AdiolG, 4-And, 17-cetoesteroids…). In my case I have hight DHT with 1.5 dutasteride but very low AdiolG.
how high?
 

GRme11

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don’t spread misinformation. he hasnt been on hrt long enough to fully recover. the prolactin is bad but it’s still early days for SG

What? Are you kidding me? We are talking for sky high levels of prolactin, not just slightly elevated! High prolactin can induce premature catagen. Also, cpa is not a good anti androgen, period. Tons of side effects, possibility to increase DHT, the elevated prolactin and the list goes on. Bicalutamide exists for a reason. He needs to redefine his regimen and address any other issues he may have. Anything can contribute to hair loss.
 

Dav1234

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Does anyone take oral corticosteroids or just topical? And any good recommendations?
 

pentobean

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can you share hair pics?
Im hoping you have thick hair and just paranoid like adri who wants perfection…
Are you at least keeping what you have??
One thing I noticed after being on hrt for a while is that my hair kind of got thinner, sort of like a woman’s hair. Thus revealing more of the bald spots. Like it’s gotten thicker than before but looks thin like a woman’s if that makes sense. Either that or I had a slight shed and didn’t notice
 

Adri23

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CPA isn't the best for hair (or prostate cancer) in most cases, that's for sure, but it totally has its perks. I personally tolerated it much better than bica and used for far longer, more than a year compared to a month on bica, that made my stomach irritated and likely caused ACTH problems (this one Im not 100% sure). In the end tho, for me CPA caused hyperprolactinemia (on 12.5mg/d), which went away after 1 tablet of Cabergoline. After that I actually tried it at 12.5mg every 3rd day (b4 switching to GNRH) and it kinda worked out and prolactin was actually in ok ranges (around 550mIU/l while on 5mg EEn).
For the perks, the main one is better skin. Basically the same as when I was using progesterone, less dry, more tighter and glowier. Prog and CPA were actually the only ones that were giving me HRT glow. Tho, I'm not sure about the nature of that glow, could be both progestogen effect on skin elasticity and circulation and increased oiliness due to elevated DHT. So that might've been a DHT glow in fact. :oops: But, jokes aside, the best skin of my life was on progestins.
The other perks (well, at least they were perks for me, because I tried girlmoding at that time) were breast development and muscle/ligament/tendon atrophy (lost 2cm of height and 1 shoe size while on it). There are some interesting mechanisms behind those, but I didn't comprehend them thoroughly, mb later when I'll have enough time.
So, overall CPA can be manageable, but only on super low dose (12.5mg EOD ,or better E3D) and it requires monitoring of liver enzymes, prolactin and DHEA-S, and also some might benefit from taking Cabergoline once every 2 or 3 weeks. It's main advantage is, IMO, hands down, best feminizing effects, compared to other AAs.
Dam you have to have a degree to use that f*****g drug. I stopped it long ago, it massacred my hair even at 12.5 mg every third day. Best anti androgen is having no balls unironically talking lmfao.
 

Adri23

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A thing im gonna try when i get my balls cut (which should be soon cause the f*** are doctors waiting for, they are f*****g necrotic) is lowering my estradiol to 250 pg/ml. I remember I had better hair back in 2023 and it was because my shbg was lower and my free estradiol was way higher, i calculated it and it all makes sense. Went from 2.11% free estradiol to 1.75%. Seems to affect my hair quite a lot. My skin was also better before.

I suspect im kinda estradiol insensitive so the more free estradiol the better outcome
 
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Adri23

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Says who=)) I can only wonder how many degrees are necessary to somehow maintain your regimen (in addition to psychiatric). xD
My regimen reveals how much I hate androgens
 

Adri23

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You need more sebum in skin IMO. Progesterone is still the best option.
How cant I have sebum with such high dht thoo? But tbh my 3a diol g is 8 ng/dl
 

Adri23

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Your DHT is not super high and your skin might metabolise too low of it, and/or no hypersensitivity to DHT in that area.
Hell yes. Another reason to have sh*t genetics. Normal skin sensitivity to androgen but high sensitivity on the scalp, I have to choose to be bald or have a grandpa dry skin with wrinkles and red spotsfrom the dryness yay.
You succeeded in degrading it for sure. =) Another reason to add Prog IMO.
f*** but I am hella afraid of getting the prog to dht pathway activation. If my dht is that high it must be due to 5ar1 working at its best from androstenedione, so if I add prog it would be a bigger issue. But yeah im I make my solution work I will add prog for sure.
 

pentobean

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Has anyone here added ghk-cu into their regiment? The results seem pretty promising and it seems quite strong especially with the collagen boost and better hair follicles
 

Seanrutty

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Both are not using HRT. One of them used her but stopped dutasteride when started hrt. Makes no sense. Also sometimes the backdoor is so strong for some ppl that they have to take more dutasteride.
[/QUOTE]
so I’m not new to hair loss but I am new to using female things for hair never tried it yet so that being said is all this Bica e2 spironolactone better then finasteride dutasteride topical finasteride topical dutasteride what’s the success story on hrt and im saying as in staying male looking male hrt dose vs finasteride dutasteride ru ectt
 

Adri23

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Just go for it, who needs hair if you have flawlesss baby skin. Babies don't even have hair, and still look cute.
Well babies dont have hair but they are cute. I am starting to age and I'm not as cute as a baby, also my face shape is dogshit that's the whole point of not going bald.
Ok I decided, from now on I'll be the ambassador of DHT glow (c).
DHT glow to the masses!
As long as you are not too sensitive to DHT and you have it in a decent range you are ok. I def dont think having my dht levels gives me any advantage honestly.
 

Adri23

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Both are not using HRT. One of them used her but stopped dutasteride when started hrt. Makes no sense. Also sometimes the backdoor is so strong for some ppl that they have to take more dutasteride.
so I’m not new to hair loss but I am new to using female things for hair never tried it yet so that being said is all this Bica e2 spironolactone better then finasteride dutasteride topical finasteride topical dutasteride what’s the success story on hrt and im saying as in staying male looking male hrt dose vs finasteride dutasteride ru ectt
If you are really 41 as it says in your profile you will have no issues looking male despite using hrt. It will absolutely work better than dutasteride and minoxidil for example. But estradiol alone might not be sufficient for some ppl and they have to add dutasteride(or keep it if you are using it)
 
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